- Basic information
- CohesinDB ID: CDBP00418830
- Locus: chr21-37351226-37351559
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Data sourse: GSE206145-NatGen2015, GSE206145-GSE177045, GSE67783
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Cell type: MCF-7, Fibroblast, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: Mau2,SA1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
94% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 56%,
"9_Het": 33%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: TRP47, TRIM28, ZFX, HIF1A, SOX11, SETDB1
- Target gene symbol (double-evidenced CRMs): VPS26C,HLCS,KCNJ15,KCNJ6,DYRK1A,TTC3
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 1
- Related genes and loops
- Related gene:
ENSG00000159267,
ENSG00000182670,
ENSG00000157538,
ENSG00000157540,
ENSG00000157542,
ENSG00000157551,
- Related loop:
chr21:36950000-36975000~~chr21:37350000-37375000,
chr21:36975000-37000000~~chr21:37350000-37375000,
chr21:37150000-37175000~~chr21:37350000-37375000,
chr21:37250000-37275000~~chr21:37350000-37375000,
chr21:37325000-37350000~~chr21:38225000-38250000,
chr21:37350000-37375000~~chr21:37450000-37475000,
chr21:37350000-37375000~~chr21:37625000-37650000,
chr21:37350000-37375000~~chr21:37650000-37675000,
chr21:37350000-37375000~~chr21:37900000-37925000,
chr21:37350000-37375000~~chr21:38275000-38300000,