- Basic information
- CohesinDB ID: CDBP00418831
- Locus: chr21-37352423-37352964
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Data sourse: GSE67783, GSE86191, GSE72082, GSE206145, ENCSR054FKH, ENCSR153HNT
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Cell type: RPE, HCT-116, Hep-G2, K-562, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
94% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 72%,
"14_ReprPCWk": 15%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: TOP2A, ZFX, BRD4, DUX4, ZNF300
- Target gene symbol (double-evidenced CRMs): KCNJ6,VPS26C,HLCS,KCNJ15,DYRK1A,TTC3
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 2
- Related genes and loops
- Related gene:
ENSG00000159267,
ENSG00000182670,
ENSG00000157538,
ENSG00000157540,
ENSG00000157542,
ENSG00000157551,
- Related loop:
chr21:36950000-36975000~~chr21:37350000-37375000,
chr21:36975000-37000000~~chr21:37350000-37375000,
chr21:37150000-37175000~~chr21:37350000-37375000,
chr21:37250000-37275000~~chr21:37350000-37375000,
chr21:37265872-37268915~~chr21:37357432-37359628,
chr21:37266235-37268923~~chr21:37357430-37359645,
chr21:37291897-37293726~~chr21:37357430-37359645,
chr21:37325000-37350000~~chr21:38225000-38250000,
chr21:37350000-37375000~~chr21:37450000-37475000,
chr21:37350000-37375000~~chr21:37625000-37650000,
chr21:37350000-37375000~~chr21:37650000-37675000,
chr21:37350000-37375000~~chr21:37900000-37925000,
chr21:37350000-37375000~~chr21:38275000-38300000,