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Basic information

CohesinDB ID: CDBP00418838

Locus: chr21-37376938-37377779

Data sourse: ENCSR000BLD, ENCSR230ZWH, GSE67783, ENCSR000BMY, ENCSR153HNT, ENCSR917QNE

Cell type: H1-hESC, GM12878, K-562, Liver, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 2% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.944

Subunit: SA1,Rad21

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 94% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "5_TxWk": 62%, "7_Enh": 31%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, SKI, PGR, CHD8, TBL1X, ZNF263, EBF1, FOXA2, CEBPA, ZFX, ZNF600, XBP1, ZBTB48, STAT1, FOXA1, ZNF770, ZBTB33, CDK9, HNF4G, ERG, RELA, HDGF, PRPF4, NOTCH1, ASCL1, ZNF341, NEUROD1, MYC, RUNX2, SMARCA4, HOMEZ, RUNX3, RAD21, TCF4, GRHL3, ZNF532, RXRA, OTX2, GATA3, ZNF48, SMAD4, TAL1, MAX, SUPT5H, CHD1, CEBPG, BCL11B, CEBPB, KLF5, ZEB1, ZNF558, KMT2A, MYB, TEAD3, TEAD1, EZH2, SMAD5, ESR1, TRIM28, MYOD1, CTCF, RBM22, TCF12, BCL11A, KLF1, SP1, LMO1, AR, HNF4A, MAFK, PAX8, NUTM1, GATA2, ZBTB26, BRD4, PHIP, JUND, FOXP1, FOXA3, GATAD2A, MLLT1, ZNF316

Target gene symbol (double-evidenced CRMs): TTC3,DYRK1A,VPS26C

Function elements

Human SNPs: .

Number of somatic mutations (coding): 49

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000182670, ENSG00000157538, ENSG00000157540,

eachgene

Deatailed information for cohesin site CDBP00418838