- Basic information
- CohesinDB ID: CDBP00418845
- Locus: chr21-37401496-37402410
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Data sourse: GSE138405, GSE62063, GSE120943, ENCSR153HNT
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Cell type: K-562, Hela-Kyoto, Monocytes, Ramos
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: NIPBL,SMC3,SA1,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
94% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 42%,
"9_Het": 24%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: CBX5, ZSCAN5C, SOX2, FOXA1, HDGF, RUNX3, PRDM1, ZNF532, THRAP3, KLF5, TRIM28, BCLAF1, RCOR2, LMO2, JUN, NUTM1, DPF2, TRIM24, DDX20, SMC1, ZNF280A, EHMT2, PDX1, XRCC3, POU5F1, TOP2A, ZNF317, ZBTB17, DUX4, MTA2, STAT1, SAP130, NBN, ARID3A, ZNF585B, OGG1, ONECUT1, HOMEZ, STAT3, RCOR1, NFE2, ZNF639, CEBPB, SPI1, ZNF644, SMARCA5, RELB, CC2D1A, CBX1, CEBPA, SMARCC1, ZNF549, BRD9, ZNF184, ARNT, ZEB2, FOS, SUPT5H, CDK8, ZNF558, ZMYM3, SETDB1, RBM22, USF1, BCL11A, BCOR, ZNF34, MLLT1, NFATC3, FOXA2, CBX3, PAF1, ZBTB33, HOXB13, KDM1A, JUNB, AHR, CHAMP1, OTX2, BATF, ZNF143, GATA1, CEBPG, SP7, NR2F1, TBX21, ZNF324, ZNF280D, NCOR1, BRD4, JUND, ZNF24, ZNF316
- Target gene symbol (double-evidenced CRMs): DYRK1A
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 7
- Number of somatic mutations (non-coding): 0
- Related genes and loops