- Basic information
- CohesinDB ID: CDBP00418847
- Locus: chr21-37405625-37405982
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Data sourse: ENCSR230ZWH, ENCSR000BKV, ENCSR879KXD, ENCSR000BMY, ENCSR917QNE
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Cell type: K-562, Liver, GM12878
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
94% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"7_Enh": 38%,
"5_TxWk": 34%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, POU2F2, CHD8, PPARG, HDAC1, ZNF263, CREM, FOXA2, PAF1, NFATC1, ZNF600, XBP1, MEIS2, WT1, SOX2, TOP2A, FOXA1, ZBTB17, ERG3, SUZ12, LEO1, ERG2, PBX2, RELA, HDGF, ZBTB2, NEUROD1, MYC, NFIC, SMARCA4, RAD21, GRHL3, SKIL, ZNF532, HIF1A, OTX2, MORC2, GATA3, PGR, ARNT, MAX, PAX5, SUPT5H, ZNF143, MITF, MED1, SP7, TEAD1, ZNF264, TRIM28, SCRT2, CCAR2, CREB1, EZH2, LMO2, ESR1, OCA2, USF2, ZNF652, CTCF, RBM22, USF1, NUTM1, MNT, AR, PAX3-FOXO1, BHLHE40, DPF2, HDAC2, REST, GATA2, NOTCH3, BRD4, FOXP1, E2F1, ZIM3, ATF1, EED
- Target gene symbol (double-evidenced CRMs): DYRK1A
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 7
- Number of somatic mutations (non-coding): 0
- Related genes and loops