- Basic information
- CohesinDB ID: CDBP00418848
- Locus: chr21-37407692-37408480
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Data sourse: ENCSR000DZP, ENCSR230ZWH, GSE138405, GSE206145, ENCSR000BMY, GSE50893, ENCSR917QNE
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Cell type: RPE, GM12892, Hela-Kyoto, GM2610, GM19240, GM12878, GM12891, Liver
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.911
- Subunit: SA1,Rad21,SA2,Mau2,SMC3
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
94% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"7_Enh": 46%,
"5_TxWk": 35%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOSL1, ZNF660, SOX2, MEIS2, XBP1, FOXA1, PBX2, LEO1, HDGF, ATF3, NFIC, CHD7, PRDM1, RUNX3, ZNF532, ATF4, SMARCE1, MITF, BACH2, MAF, ZNF121, BCLAF1, TRIM28, NFE2L2, ESR1, OCA2, CTCF, NUTM1, DPF2, SIX5, SOX6, GATAD2A, RBPJ, TFAP2C, CHD8, ZSCAN5D, ZNF263, ZBTB17, DUX4, NBN, HNF4G, ERG, NFKB2, SMARCC2, ONECUT1, MYC, SMARCA4, TSHZ1, RAD21, GRHL3, RXRA, STAT3, ZNF614, APC, IKZF1, NFE2, ZNF639, NR3C1, CEBPB, STAT5B, KMT2A, CREB1, EZH2, NFE2L1, SPI1, ZNF664, HDAC2, GATA2, FLI1, RELB, ZIM3, RUNX1, MAFG, HDAC1, ZFX, POU4F2, TRIM22, NSD2, ZNF384, RUNX2, CDK6, GATA4, ARNT, BACH1, ATF2, HMGB2, ZEB2, PBX3, SUPT5H, CDK8, PML, C11orf30, ZNF136, RBM22, MAFK, SP1, BCL11A, HNF4A, REST, ATF7, ASH2L, PHIP, FOXP1, PRDM6, MLLT1, FOXA2, EBF1, PAF1, NFATC1, ZNF600, E2F8, GTF2B, WT1, MAFF, ZBTB33, CDK9, ZNF580, YY1, RELA, JUNB, SKIL, OTX2, BATF, ZNF143, NCOA3, NR2F2, NR2F1, PKNOX1, ZBTB6, NFKB1, TBX21, AR, ZBTB40, ZBTB26, NOTCH3, BRD4, JUND, ZNF316
- Target gene symbol (double-evidenced CRMs): DYRK1A
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 21
- Number of somatic mutations (non-coding): 0
- Related genes and loops