- Basic information
- CohesinDB ID: CDBP00418857
- Locus: chr21-37427162-37427392
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Data sourse: ENCSR000BLD, GSE72082, ENCSR000BLS
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Cell type: H1-hESC, Hep-G2
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
94% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 72%,
"4_Tx": 20%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: NFIA, PGR, HMG20A, SOX2, MEIS2, XBP1, FOXA1, LEO1, RXRB, HNRNPK, TFAP4, CDK2, ATF3, NFIC, ZNF362, CHD7, PRDM1, RUNX3, ZNF532, ATF4, MXD4, SMARCE1, TP63, ZNF467, CDX2, MAF, ELF1, TRIM28, TEAD1, KLF6, SNAI2, KLF10, SMAD5, ESR1, OCA2, HNF1B, PITX3, RCOR2, CTCF, TCF12, JUN, EP300, NUTM1, E4F1, BAF155, LMO1, GATA6, SOX5, DPF2, ZNF714, IRF4, TRIM24, SOX6, E2F1, ZNF528, TEAD4, FOXA3, GATAD2A, EHMT2, TFAP2C, EED, MLX, GLIS1, POU2F2, NANOG, CHD8, BRD3, POU5F1, TOP2A, CDK7, ZNF317, MTA2, DUX4, ZBTB48, STAT1, ZSCAN5A, ZSCAN21, ZNF134, MLLT3, SAP130, ZBTB17, PHB2, TBP, HNF4G, ERG, OGG1, MYC, SMARCA4, ARID1B, RAD21, HOMEZ, GRHL3, RXRA, NKX2-1, GABPA, STAT3, XRCC5, ZNF614, NKX3-1, ZNF398, IKZF1, RCOR1, MIER3, NR2F6, VDR, NR3C1, CEBPB, ZNF85, KMT2A, CREB1, EZH2, FEZF1, ZNF652, EBF3, ZNF48, SPI1, MIXL1, IRF1, HDAC2, GATA2, ZNF644, SIX2, FLI1, ZNF490, NFIL3, ZIM3, ETV5, CC2D1A, RUNX1, ZNF585A, SMC1A, BCL6, HDAC1, LDB1, CEBPA, NKX2-2, SOX13, ZFX, POU4F2, SIN3A, SMAD3, ZNF770, ERG3, ZNF792, PRDM10, RARA, ZNF384, NOTCH1, ZNF133, RUNX2, GATA4, ARNT, PBX4, ATF2, PRDM9, HMBOX1, ZEB2, SMAD4, CBFA2T3, FOXM1, ZNF10, SUPT5H, CDK8, FOS, GMEB1, TEAD3, PML, CEBPD, MYB, SCRT2, ZMYM3, ZNF331, PIAS1, NCOA1, STAT5A, RBM22, NUP98-HOXA9, BCL11A, SP1, MAFK, HNF4A, USF1, REST, ZBTB7A, RBM25, ATF7, ASH2L, HOXA9, PHIP, TCF3, FOXP1, PRDM6, ZNF623, SMC3, STAT2, MLLT1, CBFA2T2, PPARG, FOXA2, CBX3, CHD2, PAF1, NFATC1, MIER2, ZNF692, ZNF600, WT1, MAFF, FOXF1, ZBTB33, CDK9, HOXB13, KDM1A, YY1, RELA, NEUROD1, ZNF148, AHR, CHAMP1, ISL1, ZNF830, BRCA1, HIF1A, TCF4, OTX2, GATA3, BHLHE22, TAL1, MAX, SPIB, GATA1, ZNF143, NRIP1, HAND2, TLE3, KLF4, ZNF592, CEBPG, GFI1B, ZNF281, NR2F2, NCOA3, BCL11B, TCF7L2, NR2F1, TP53, PKNOX1, MYOD1, PHOX2B, T, BRD2, PHF5A, ELF3, BHLHE40, AR, ARID4B, PAX3-FOXO1, ZBTB40, ZBTB42, EGR1, ZBTB26, NCOR1, NOTCH3, BRD4, SCRT1, JUND, MAZ, ZNF24, ZNF316
- Target gene symbol (double-evidenced CRMs): TTC3,VPS26C,DYRK1A
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 11
- Number of somatic mutations (non-coding): 0
- Related genes and loops