- Basic information
- CohesinDB ID: CDBP00418887
- Locus: chr21-37489319-37490070
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Data sourse: ENCSR000BLD, ENCSR230ZWH, GSE72082, ENCSR760NPX, ENCSR000BLY, GSE105028, GSE25021, ENCSR917QNE, ENCSR000BTU, ENCSR000BKV, GSE138405, GSE101921, GSE94872, ENCSR000BLS, GSE206145, ENCSR000ECE, ENCSR000BMY, ENCSR000EHX, GSE97394, ENCSR000BTQ, GSE129526, GSE68388, GSE50893, GSE73207
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Cell type: GM2610, Liver, HuCC-T1, H9-hESC, RPE, Ishikawa, K-562, H1-hESC, SNYDER, TF-1, GM12878, GM2588, GM12891, SK-N-SH, HUES64, MCF-7, Hela-Kyoto, HCT-116, Hep-G2, A-549, HUVEC, HCAEC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 8% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.756
- Subunit: SMC3,SA1,Rad21,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
94% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 56%,
"4_Tx": 34%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, FOXO1, PGR, SMC1A, PPARG, FOXA2, CEBPA, PAF1, SOX2, ZFX, XBP1, ZSCAN16, ZBTB48, DUX4, FOXA1, HOXB13, ERG, RELA, ZNF384, OGG1, JUNB, EZH1, CDK6, SMARCA4, MYC, GATA4, RAD21, PRDM1, GRHL3, HIF1A, ZNF532, ARNT, GABPA, SMARCE1, PAX5, TAL1, ZNF10, SUPT5H, ZNF143, MITF, GATA1, AGO2, NRIP1, MED1, STAT3, CEBPG, CEBPB, NCOA3, EZH2, SMAD5, OCA2, C11orf30, PHOX2B, JUN, RBM22, CTCF, SPI1, NUTM1, BCL11A, ZNF664, AR, PAX3-FOXO1, GATA2, IRF4, NCOR1, HOXA9, BRD4, SCRT1, FOXP1, ZNF528, SMC3, ZNF554, ZZZ3, STAG1, RBPJ
- Target gene symbol (double-evidenced CRMs): TTC3,KCNJ6,HLCS,VPS26C,DYRK1A
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 22
- Number of somatic mutations (non-coding): 2
- Related genes and loops