Deatailed information for cohesin site CDBP00418889

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  • Basic information
  • CohesinDB ID: CDBP00418889
  • Locus: chr21-37496386-37498023
  • Data sourse: ENCSR000BLD, GSE206145-GSE177045, GSE104888, ENCSR230ZWH, GSE72082, ENCSR000BSB, ENCSR501LQA, GSE126634, ENCSR760NPX, ENCSR000EGW, ENCSR000BLY, ENCSR404BPV, ENCSR150EFU, GSE105028, GSE121355, GSE103477, GSE62063, GSE131606, ENCSR330ELC, GSE108869, GSE25021, ENCSR000BUC, ENCSR917QNE, ENCSR000EFJ, ENCSR000BTU, GSE93080, ENCSR000DZP, ENCSR000EAC, GSE143937, ENCSR000BKV, GSE138405, GSE76893, GSE101921, ENCSR806UKK, GSE152721, GSE206145-NatGen2015, ENCSR198ZYJ, GSE138105, GSE130135, ENCSR199XBQ, ENCSR703TNG, GSE116344, GSE94872, ENCSR895JMI, ENCSR000EEG, ENCSR193NSH, ENCSR768DOX, ENCSR879KXD, ENCSR000BLS, ENCSR000EHW, GSE85526, ENCSR000ECE, ENCSR247LSH, ENCSR000BMY, ENCSR000EHX, ENCSR620NWG, ENCSR748MVX, ENCSR767DFK, ENCSR807WAC, ENCSR495WGO, ENCSR981FDC, ENCSR984DZW, GSE97394, ENCSR217ELF, ENCSR000BTQ, GSE105004, ENCSR167MTG, ENCSR853VWZ, ENCSR956LGB, ENCSR944ZCT, GSE110061, GSE129526, ENCSR000HPG, ENCSR676MJK, GSE155324, ENCSR335RKQ, ENCSR054FKH, ENCSR537EFT, ENCSR000EDE, GSE68388, GSE206145, GSE126990, GSE50893, ENCSR000ECS
  • Cell type: MDM, RH4, GM10847, GM2610, SLK, GM19240, Liver, HuCC-T1, H9-hESC, RPE, GM2630, HMEC, Fibroblast, HEKn, Ishikawa, GM12890, HeLa-S3, GM2255, IMR-90, K-562, GM18486, DKO, GM18526, H1-hESC, SNYDER, GM18505, Lymphoblast, GM12878, GM12891, GM2588, SK-N-SH, GM19239, GM19193, HAP1, GM19099, HUES64, MCF-7, GM12892, Ramos, Hela-Kyoto, HCT-116, THP-1, HEK293T, Hep-G2, Neurons-H1, A-549, HUVEC, HCAEC, GM19238, HeLa, GM18951
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 45% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.422
  • Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2,SMC3
  • CTCF binding site: CTCF CTCF motif: True
  • Genomic location: Intragenic
  • 3D genome
  • TAD boundary: Boundary
  • Chromatin hubs: non-Hub
  • Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True
  • Compartment: 94% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): True
  • Chromatin annotation: "5_TxWk": 59%, "4_Tx": 30%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: ZNF394, GLIS1, POU2F2, SMC1A, POU5F1, ZNF660, PAF1, ZFX, GTF2B, DUX4, FOXA1, ZNF205, ZNF770, SRF, SAP130, CDK9, HOXB13, PRDM10, YY1, ZBTB2, ATF3, MYC, OSR2, RFX1, RAD21, HOMEZ, CHD7, ZNF532, RXRA, OTX2, ZEB2, GABPA, ZSCAN4, SUPT5H, ZNF736, CEBPB, SMAD1, STAG1, ZNF3, ESR1, TP53, KLF16, CTCF, RBM22, PHOX2B, BCL11A, NUTM1, MIXL1, REST, IRF4, ZNF777, DRAP1, BRD4, SMARCA5, CLOCK, FOXP1, SMC1, MRTFB, SMC3, ZZZ3, PDX1
  • Target gene symbol (double-evidenced CRMs): TTC3,HLCS,VPS26C,KCNJ6,DYRK1A
  • Function elements
  • Human SNPs: .
  • Number of somatic mutations (coding): 110
  • Number of somatic mutations (non-coding): 10
  • Related genes and loops
  • Related gene: ENSG00000159267, ENSG00000182670, ENSG00000157538, ENSG00000157540, ENSG00000157542,
  • Related loop: chr21:36975000-37000000~~chr21:37475000-37500000, chr21:37150000-37175000~~chr21:37500000-37525000, chr21:37166095-37167716~~chr21:37496458-37497998, chr21:37200000-37225000~~chr21:37475000-37500000, chr21:37225000-37250000~~chr21:37475000-37500000, chr21:37475000-37500000~~chr21:37625000-37650000, chr21:37496463-37497911~~chr21:37581835-37583666, chr21:37500000-37525000~~chr21:37625000-37650000,
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