- Basic information
- CohesinDB ID: CDBP00418894
- Locus: chr21-37506066-37506334
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Data sourse: GSE67783, ENCSR153HNT, GSE86191
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Cell type: K-562, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
95% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"4_Tx": 89%,
"5_TxWk": 8%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: ZNF468, FOSL1, PGR, E2F7, SOX2, HMGN3, MEIS2, XBP1, FOXA1, LEO1, PBX2, MLL4, HDGF, ATF3, NFIC, BMI1, ZNF362, CHD7, PRDM1, RUNX3, ZNF532, ATF4, GLYR1, SMARCE1, PAX5, BACH2, MYOG, JMJD1C, TEAD1, SNAI2, NFE2L2, ESR1, OCA2, PITX3, HDAC8, CTCF, TCF12, JUN, EP300, NUTM1, KLF1, BAF155, GATA6, DPF2, SOX4, TRIM24, IRF4, SOX6, E2F1, ZNF677, ZNF528, TEAD4, KMT2B, PDX1, TFAP2C, EED, RBPJ, NANOG, CHD8, POU2F2, POU5F1, MYCN, TOP2A, ZNF317, MTA2, ZBTB48, DUX4, ZSCAN5A, BAHD1, ARID3A, ERG, HOXC5, OGG1, SMARCC2, MYC, SMARCA4, RFX1, ARID1B, RAD21, HOMEZ, GRHL3, RXRA, NKX2-1, GABPA, STAT3, NKX3-1, IKZF1, NFE2, RCOR1, VDR, NR3C1, ESRRA, CEBPB, EZH2, GRHL2, ZNF652, EBF3, NFE2L1, SPI1, IRF1, GATA2, FLI1, HEXIM1-CDK9, MRTFB, NFYB, ZNF554, ATF1, RUNX1, SMC1A, MAFG, HDAC1, CEBPA, NKX2-2, LDB1, ZFX, POU4F2, SMAD3, PCBP2, ERG3, MEF2A, RARA, ZNF384, ZNF35, ZNF133, RUNX2, GATA4, ARNT, BACH1, NRF1, ATF2, ZEB2, HMBOX1, NFYA, CBFA2T3, MAFB, FOXM1, SUPT5H, FOS, CDK8, MED1, TEAD3, ZNF558, CEBPD, SCRT2, PIAS1, ZNF3, C11orf30, L3MBTL2, SETDB1, TBX5, RBM22, MAFK, BCL11A, HNF4A, NR4A1, ARID2, REST, ZBTB7A, CCNT2, ATF7, POU2F3, FOXP1, AATF, SMC3, MLLT1, STAG1, ZNF816, PAX7, TRP47, ZNF283, MEF2B, PPARG, FOXA2, TBL1X, EBF1, CREM, PAF1, NFATC1, ZSCAN16, MAFF, WT1, FOXF1, MEF2C, CDK9, HOXB13, ZNF318, KDM1A, YY1, RELA, TARDBP, JUNB, AHR, NEUROD1, ISL1, SP140, ZNF830, HIF1A, GATA3, TAL1, MAX, SPIB, ZNF143, AGO2, GATA1, MTA1, HAND2, PLAG1, ZNF592, NCOA3, NR2F1, KDM5B, TP53, ZNF334, PHOX2B, AR, PAX3-FOXO1, ZBTB26, RNF2, IKZF2, BRD4, JUND, SCRT1, ILF3, CLOCK, MAZ, ZZZ3, ZNF316, FOSL2
- Target gene symbol (double-evidenced CRMs): KCNJ6,TTC3,DYRK1A
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 318
- Number of somatic mutations (non-coding): 29
- Related genes and loops