- Basic information
- CohesinDB ID: CDBP00418904
- Locus: chr21-37528156-37530049
-
Data sourse: ENCSR000BLD, GSE72082, ENCSR000FAD, ENCSR000EGW, GSE105028, GSE25021, ENCSR000EDW, GSE143937, GSE67783, ENCSR000BKV, GSE86191, GSE76893, GSE120943, ENCSR000EEG, GSE98367, ENCSR000BLS, GSE206145, ENCSR000ECE, GSE97394, ENCSR167MTG, ENCSR054FKH, ENCSR153HNT
-
Cell type: RPE, H1-hESC, HCT-116, Monocytes, Hep-G2, HUES64, K-562, HSPC, Macrophage, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 7% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.889
- Subunit: SA1,Rad21,SMC1,SA2,SMC3
-
CTCF binding site: CTCF
CTCF motif: True
- Genomic location: TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: non-Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
95% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 33%,
"14_ReprPCWk": 32%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: GLIS1, ADNP, POU2F2, CHD8, SMC1A, TBL1X, MYCN, PAF1, ZFX, ID3, XBP1, ZBTB48, WT1, STAT1, ZNF770, PBX2, LEO1, CDK9, ZKSCAN1, PRDM10, ERG, YY1, RELA, CREBBP, ZNF384, KDM1A, ZBTB2, SMARCA4, CTCFL, RAD21, SP140, ZIC2, HIF1A, GRHL3, ZFP36, ARNT, ZNF48, XRCC5, ZNF10, ZNF143, IKZF1, RCOR1, PLAG1, NR3C1, GFI1B, ZNF121, RBM39, SNAI2, ZMYM3, NFE2L2, ZNF3, EZH2, ZNF652, CTCF, JUN, AR, ARID2, REST, ZBTB7A, HDAC2, RBM25, HSF1, MXI1, SCRT1, SMARCA5, BCOR, MAZ, SMC3, ZNF24, STAG1, AHR
- Target gene symbol (double-evidenced CRMs): TTC3,DYRK1A,VPS26C,KCNJ6
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 8
- Related genes and loops
- Related gene:
ENSG00000182670,
ENSG00000157538,
ENSG00000157540,
ENSG00000157542,
- Related loop:
chr21:37050000-37075000~~chr21:37525000-37550000,
chr21:37150000-37175000~~chr21:37500000-37525000,
chr21:37200000-37225000~~chr21:37525000-37550000,
chr21:37225000-37250000~~chr21:37525000-37550000,
chr21:37375000-37400000~~chr21:37525000-37550000,
chr21:37500000-37525000~~chr21:37625000-37650000,
chr21:37525000-37550000~~chr21:37625000-37650000,
chr21:37525000-37550000~~chr21:38075000-38100000,
chr21:37525000-37550000~~chr21:38150000-38175000,
chr21:37527492-37529167~~chr21:37581619-37583658,
chr21:37532652-37534151~~chr21:37556775-37558385,