- Basic information
- CohesinDB ID: CDBP00418908
- Locus: chr21-37535724-37536412
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Data sourse: GSE67783, ENCSR153HNT, GSE86191
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Cell type: K-562, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21
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CTCF binding site: non-CTCF
CTCF motif: True
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
95% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"9_Het": 38%,
"14_ReprPCWk": 31%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: MYCN, ID3, ZFX, XBP1, ZBTB48, WT1, FOXA1, ZNF770, RELA, CREBBP, SP140, GRHL3, ATF2, PRDM9, ZNF736, MED1, ZFP69B, EZH2, ZNF3, ESR1, SETDB1, TBX5, ZNF257, E2F6, ATF7, RNF2, JUND, ZIM3, ZNF24
- Target gene symbol (double-evidenced CRMs): DYRK1A,TTC3,VPS26C,KCNJ6
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 4
- Related genes and loops
- Related gene:
ENSG00000182670,
ENSG00000157538,
ENSG00000157540,
ENSG00000157542,
- Related loop:
chr21:37050000-37075000~~chr21:37525000-37550000,
chr21:37200000-37225000~~chr21:37525000-37550000,
chr21:37225000-37250000~~chr21:37525000-37550000,
chr21:37375000-37400000~~chr21:37525000-37550000,
chr21:37525000-37550000~~chr21:37625000-37650000,
chr21:37525000-37550000~~chr21:38075000-38100000,
chr21:37525000-37550000~~chr21:38150000-38175000,
chr21:37532652-37534151~~chr21:37556775-37558385,