- Basic information
- CohesinDB ID: CDBP00418911
- Locus: chr21-37538100-37538700
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Data sourse: GSE116344, ENCSR153HNT
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Cell type: K-562, RH4
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
95% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 71%,
"14_ReprPCWk": 22%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, NFIA, FOSL1, CBX5, SOX2, SUZ12, ATF3, NFIC, ZNF362, PRDM1, ATF4, SMARCE1, TP63, ELF1, TRIM28, TEAD1, TP73, CTCF, EP300, E4F1, MNT, DPF2, TRIM24, SOX6, TEAD4, TFAP2C, GLIS1, CHD8, ZSCAN5D, POU5F1, MYCN, TOP2A, ID3, CTBP1, ZBTB48, ZSCAN5A, DUX4, HINFP, ZNF205, SRF, MYC, SMARCA4, ARID1B, ZNF398, IKZF1, RCOR1, LEF1, NR2F6, NR3C1, CEBPB, ESRRA, ZNF652, HES1, SPI1, HDAC2, GATA2, ZNF644, SMARCA5, EP400, ATF1, CC2D1A, RUNX1, CBX1, HDAC1, CEBPA, SOX13, ZNF534, ZFX, TET2, PRDM10, MYBL2, ZNF384, GATA4, OSR2, NRF1, HMBOX1, SMAD4, FOXM1, CBFA2T3, NR2C1, CDK8, MED1, TEAD3, ZMYM3, VEZF1, TAF7, NCOA1, L3MBTL2, SETDB1, TBX5, SP1, NR4A1, REST, ZBTB7A, RBM25, ATF7, ASH2L, AFF1, BCOR, AATF, SMC3, MLLT1, STAG1, PTTG1, CBX3, MTA3, CREM, RBBP5, WT1, KDM1A, YY1, RELA, ZNF148, SP140, ZFP36, SKIL, ZIC2, ZNF519, TAL1, MAX, GATA1, GFI1B, NR2F2, NCOA3, NR2F1, KDM5B, TP53, TAF1, ZBTB40, NCOR1, RNF2, JUND, ILF3, BRD4, MAZ, IRF9, MEF2D
- Target gene symbol (double-evidenced CRMs): DYRK1A,KCNJ6,VPS26C,TTC3
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 1
- Related genes and loops
- Related gene:
ENSG00000182670,
ENSG00000157538,
ENSG00000157540,
ENSG00000157542,
- Related loop:
chr21:37050000-37075000~~chr21:37525000-37550000,
chr21:37200000-37225000~~chr21:37525000-37550000,
chr21:37225000-37250000~~chr21:37525000-37550000,
chr21:37375000-37400000~~chr21:37525000-37550000,
chr21:37525000-37550000~~chr21:37625000-37650000,
chr21:37525000-37550000~~chr21:38075000-38100000,
chr21:37525000-37550000~~chr21:38150000-38175000,
chr21:37532652-37534151~~chr21:37556775-37558385,