- Basic information
- CohesinDB ID: CDBP00418914
- Locus: chr21-37549977-37550331
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Data sourse: GSE67783, GSE111913, ENCSR153HNT
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Cell type: K-562, RT-112, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
95% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 49%,
"5_TxWk": 26%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: SOX11, ZNF146, ZFX
- Target gene symbol (double-evidenced CRMs): HLCS,TTC3,VPS26C,KCNJ6,DYRK1A
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 2
- Related genes and loops
- Related gene:
ENSG00000159267,
ENSG00000182670,
ENSG00000157538,
ENSG00000157540,
ENSG00000157542,
- Related loop:
chr21:36950000-36975000~~chr21:37550000-37575000,
chr21:36975000-37000000~~chr21:37550000-37575000,
chr21:37050000-37075000~~chr21:37525000-37550000,
chr21:37200000-37225000~~chr21:37525000-37550000,
chr21:37200000-37225000~~chr21:37550000-37575000,
chr21:37225000-37250000~~chr21:37525000-37550000,
chr21:37225000-37250000~~chr21:37550000-37575000,
chr21:37250000-37275000~~chr21:37550000-37575000,
chr21:37375000-37400000~~chr21:37525000-37550000,
chr21:37525000-37550000~~chr21:37625000-37650000,
chr21:37525000-37550000~~chr21:38075000-38100000,
chr21:37525000-37550000~~chr21:38150000-38175000,
chr21:37546322-37547628~~chr21:37581687-37583761,
chr21:37550000-37575000~~chr21:37650000-37675000,
chr21:37550000-37575000~~chr21:38350000-38375000,