- Basic information
- CohesinDB ID: CDBP00418925
- Locus: chr21-37573339-37573876
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Data sourse: GSE206145, GSE67783
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Cell type: RPE, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 0% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
95% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 69%,
"14_ReprPCWk": 27%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, POU2F2, SMC1A, PPARG, ZSCAN5D, MYCN, CHD8, CEBPA, HDAC1, ZFX, MEIS2, CBX3, TEAD4, WT1, ZBTB48, SMAD3, ZSCAN5A, ZNF563, SAP130, SP5, PBX2, RXRB, HOXB13, TBP, ZNF300, KDM1A, TFAP4, RELA, HDGF, PBX1, HNF4G, CDK6, RAD21, SP140, GRHL3, HIF1A, STAT3, MAX, XRCC5, CBFA2T3, GATA1, TAL1, APC, HNRNPH1, ZNF667, MED1, ZEB1, ELF1, ZNF121, TEAD3, NEUROG2, NR2F1, ZNF3, ESR1, OCA2, LMO2, PKNOX1, L3MBTL2, MYOD1, CTCF, TCF12, ELF3, TFE3, ARID4B, AR, CBFA2T2, HNF4A, DPF2, ZNF479, ZSCAN29, EGR1, NCOR1, NOTCH3, BRD4, TCF3, MAZ, SMC3, STAG1, AHR
- Target gene symbol (double-evidenced CRMs): VPS26C,KCNJ6,HLCS,TTC3
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 2
- Related genes and loops
- Related gene:
ENSG00000159267,
ENSG00000182670,
ENSG00000157538,
ENSG00000157542,
- Related loop:
chr21:36950000-36975000~~chr21:37550000-37575000,
chr21:36975000-37000000~~chr21:37550000-37575000,
chr21:37150000-37175000~~chr21:37575000-37600000,
chr21:37200000-37225000~~chr21:37550000-37575000,
chr21:37225000-37250000~~chr21:37550000-37575000,
chr21:37225000-37250000~~chr21:37575000-37600000,
chr21:37250000-37275000~~chr21:37550000-37575000,
chr21:37250000-37275000~~chr21:37575000-37600000,
chr21:37550000-37575000~~chr21:37650000-37675000,
chr21:37550000-37575000~~chr21:38350000-38375000,