- Basic information
- CohesinDB ID: CDBP00418934
- Locus: chr21-37592031-37593523
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Data sourse: ENCSR000BLD, ENCSR000BTU, GSE67783, GSE105028, GSE101921, ENCSR000ECE, ENCSR153HNT, GSE83726, GSE97394, GSE64758
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Cell type: H1-hESC, RH4, Ishikawa, HCAEC, H9-hESC, K-562, HSPC, HUES64
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 4% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.911
- Subunit: NIPBL,SA1,Rad21,SMC1,SA2
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
95% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 45%,
"14_ReprPCWk": 19%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: ZSCAN5C, SOX2, XBP1, FOXA1, SUZ12, NFIC, CHD7, MORC2, PAX5, ZNF121, LMO2, ESR1, OCA2, CTCF, TCF12, EP300, ZNF33A, RYBP, E2F6, E2F4, ZNF528, SMC1, TEAD4, NANOG, CHD8, POU2F2, ZSCAN5D, MYCN, POU5F1, ID3, CTBP1, DUX4, ZBTB48, SP4, ETS1, MYC, EOMES, SMARCA4, RAD21, GRHL3, GABPA, APC, IKZF1, NR2F6, NR3C1, SRSF3, CREB1, EZH2, BMPR1A, GRHL2, HDAC2, GATA2, FLI1, SMC1A, ZFX, SMAD3, ZNF770, CBX8, ERG3, TET2, SMARCC1, ZNF18, ZNF384, NOTCH1, SMAD2, OSR2, ARNT, BACH1, ATF2, SMAD4, FOXM1, ETV6, CHD1, MED1, ZNF680, SMAD1, L3MBTL2, TBX5, USF1, BCL11A, NIPBL, SP1, NKX2-5, REST, ZBTB7A, ASH2L, PCGF2, BCOR, FOXP1, STAG1, ZNF207, WT1, ZBTB33, KDM1A, YY1, RELA, MCM3, SP140, ZIC2, HIF1A, MGA, TAL1, MAX, ZNF143, PLAG1, KLF4, NCOA3, NR2F1, ZNF334, T, AR, TAF1, HSF1, RNF2, BRD4, ILF3, MAZ
- Target gene symbol (double-evidenced CRMs): VPS26C,TTC3
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 11
- Related genes and loops