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Basic information

CohesinDB ID: CDBP00418943

Locus: chr21-37619546-37620117

Data sourse: ENCSR000BLD, GSE72082, GSE105028, GSE131606, GSE25021, GSE108869, GSE115602, GSE93080, ENCSR000DZP, ENCSR000EAC, ENCSR000BKV, GSE138405, GSE76893, GSE101921, GSE206145-NatGen2015, ENCSR703TNG, GSE85526, ENCSR000BTQ, GSE105004, GSE129526, GSE111913, ENCSR000EDE, ENCSR153HNT, GSE68388, GSE126990, GSE50893, ENCSR000ECS

Cell type: HuCC-T1, H9-hESC, GM2630, HMEC, Fibroblast, HEKn, GM12890, HeLa-S3, GM2255, K-562, DKO, H1-hESC, GM12878, RT-112, MCF-7, GM12892, Hela-Kyoto, HCT-116, MCF-10A, GM19238, HeLa

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 12% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.767

Subunit: SA1,Rad21,SMC1,SMC3ac,SA2,SMC3

CTCF binding site: CTCF CTCF motif: False

Genomic location: TES

3D genome

TAD boundary: Boundary

Chromatin hubs: non-Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 95% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 48%, "14_ReprPCWk": 27%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: PGR, MEIS2, XBP1, FOXA1, PBX2, ZFHX2, HDGF, ATF3, ZNF532, TP63, LMO2, ESR1, OCA2, CTCF, JUN, BAF155, NUTM1, SOX6, SMC1, ZNF350, TFAP2C, EED, GLIS1, CHD8, BRD1, ZSCAN5D, MYCN, POU5F1, RUNX1T1, KDM4C, TOP2A, ZBTB48, DUX4, NBN, ERG2, ERG, MYC, RFX1, RAD21, GRHL3, GABPA, STAT3, NKX3-1, PRDM14, IKZF1, NR3C1, ZNF750, CEBPB, EZH2, GRHL2, GATA2, GATAD2B, SIX2, FLI1, RELB, NCOA2, RUNX1, SMC1A, NKX2-2, ZFX, TET2, CBX8, ERG3, RUNX2, GATA4, ARNT, SOX11, ATF2, HMBOX1, FOXM1, FOS, GMEB1, PIAS1, REST, SMC3, MLLT1, STAG1, STAG2, NFATC3, CBFA2T2, MEF2B, FOXA2, EBF1, ZSCAN16, WT1, HOXB13, YY1, RELA, JUNB, SP140, HIF1A, BATF, MAF1, MAX, MTA1, ZNF512, KDM5B, ZNF687, PKNOX1, ZNF334, NFKB1, EGR2, BHLHE40, AR, ZNF366, RNF2, NOTCH3, BRD4, MAZ

Target gene symbol (double-evidenced CRMs): VPS26C,KCNJ6

Function elements

Human SNPs: .

Number of somatic mutations (coding): 2

Number of somatic mutations (non-coding): 2

Related genes and loops

Related gene: ENSG00000157538, ENSG00000157542,

eachgene

Deatailed information for cohesin site CDBP00418943