Deatailed information for cohesin site CDBP00418944
Check detailed explainations here
- Basic information
- CohesinDB ID: CDBP00418944
- Locus: chr21-37620432-37620693
- Data sourse: GSE206145, GSE206145-NatGen2015
- Cell type: RPE, Fibroblast
- DNA Sequence of binding site: UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: Mau2
- CTCF binding site: non-CTCF CTCF motif: False
- Genomic location: TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: non-Hub
- Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True
- Compartment: 95% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 51%,
"14_ReprPCWk": 29%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2). - Co-bound Transcriptional factors: PGR, SOX2, XBP1, FOXA1, PBX2, TSC22D4, ATF3, NFIC, CHD7, ZNF532, PAX5, CDX2, TEAD1, TRIM28, ZNF217, ESR1, CTCF, TCF12, JUN, EP300, NUTM1, GATA6, DPF2, E2F6, IRF4, SMC1, TFAP2C, RBPJ, POU2F2, CHD8, MYCN, TOP2A, CTBP1, MTA2, ZBTB48, ERG, NFKB2, ETS1, MYC, GRHL3, BATF3, XRCC5, IKZF1, CEBPB, ESRRA, STAT5B, TRPS1, SPI1, HDAC2, FLI1, SMARCA5, RELB, RUNX1, SIN3A, ZFX, POU4F2, CBX8, TRIM22, PRDM10, CREBBP, ZNF384, ARNT, TFDP1, ATF2, PRDM9, FOXM1, MAFB, NR2C1, FOS, ETV6, PBX3, MED1, ZEB1, SP1, BCL11A, ATF7, CTBP2, SMC3, STAG1, MEF2B, PPARG, TBL1X, EBF1, WT1, HOXB13, BCL3, YY1, RELA, JUNB, SP140, ZFP36, HIF1A, SKIL, GATA3, BATF, TAL1, MAX, ZNF143, NCOA3, NR2F2, NR2F1, ZNF687, PKNOX1, ZNF334, NFKB1, TBX21, BHLHE40, AR, PAX3-FOXO1, HSF1, NOTCH3, BRD4, IKZF2, MAZ, AHR
- Target gene symbol (double-evidenced CRMs): VPS26C,KCNJ6
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 2
- Number of somatic mutations (non-coding): 2
- Related genes and loops
- Related gene: ENSG00000157538, ENSG00000157542,
- Related loop: chr21:34350000-34375000~~chr21:37600000-37625000, chr21:36975000-37000000~~chr21:37625000-37650000, chr21:37150000-37175000~~chr21:37625000-37650000, chr21:37175000-37200000~~chr21:37625000-37650000, chr21:37200000-37225000~~chr21:37625000-37650000, chr21:37225000-37250000~~chr21:37600000-37625000, chr21:37225000-37250000~~chr21:37625000-37650000, chr21:37250000-37275000~~chr21:37625000-37650000, chr21:37350000-37375000~~chr21:37625000-37650000, chr21:37450000-37475000~~chr21:37625000-37650000, chr21:37475000-37500000~~chr21:37625000-37650000, chr21:37500000-37525000~~chr21:37625000-37650000, chr21:37525000-37550000~~chr21:37625000-37650000,
Tools:
- Assay
