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Basic information

CohesinDB ID: CDBP00418947

Locus: chr21-37626527-37627532

Data sourse: ENCSR230ZWH, GSE206145, GSE83726, GSE68388, GSE116344, ENCSR917QNE

Cell type: RPE, Liver, RH4, HuCC-T1

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 2% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.956

Subunit: Mau2,Rad21,SMC1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: TES

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 95% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 36%, "14_ReprPCWk": 25%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: POU2F2, RELA, ATF3, MYC, ZFP36, DPF1, MAX, GATA1, IKZF1, CDK8, PLAG1, ELF1, SCRT2, L3MBTL2, USF2, ELF4, USF1, E4F1, DPF2, REST, RAD51, BRD4, SCRT1

Target gene symbol (double-evidenced CRMs): KCNJ6,HLCS,DYRK1A,TTC3,VPS26C

Function elements

Human SNPs: .

Number of somatic mutations (coding): 28

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000159267, ENSG00000182670, ENSG00000157538, ENSG00000157540, ENSG00000157542,

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Deatailed information for cohesin site CDBP00418947