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Basic information

CohesinDB ID: CDBP00418956

Locus: chr21-37649610-37650298

Data sourse: GSE67783, GSE111913, ENCSR153HNT, GSE86191

Cell type: K-562, RT-112, HCT-116, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.956

Subunit: SA1,Rad21,SMC1

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 95% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "14_ReprPCWk": 47%, "15_Quies": 41%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: PGR, FOXA2, MYCN, POU5F1, RUNX1T1, ID3, ZFX, NME2, XBP1, ZSCAN5D, WT1, ZBTB48, RELA, NEUROD1, MCM5, ZBTB5, MCM3, SP140, ZNF532, OTX2, PRDM9, NR3C1, EZH2, ESR1, CTCF, TCF12, NUTM1, AR, HNRNPLL, BRD4, FOXP1, MAZ

Target gene symbol (double-evidenced CRMs): TTC3,DYRK1A,KCNJ6,VPS26C,HLCS

Function elements

Human SNPs: .

Number of somatic mutations (coding): 8

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000159267, ENSG00000182670, ENSG00000157538, ENSG00000157540, ENSG00000157542,

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Deatailed information for cohesin site CDBP00418956