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Basic information

CohesinDB ID: CDBP00418964

Locus: chr21-37670538-37671794

Data sourse: GSE111913, GSE206145, ENCSR335RKQ, GSE101921, GSE206145-NatGen2015, GSE68388, ENCSR495WGO

Cell type: RPE, Fibroblast, A-549, HCAEC, RT-112, HuCC-T1

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 6% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.933

Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2,SMC3

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 95% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "14_ReprPCWk": 39%, "15_Quies": 26%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: PPARG, FOXA2, TOP2A, ZFX, SMAD3, ZBTB48, WT1, FOXA1, PBX2, MLL4, ERG, RELA, ETS1, RUNX2, SP140, PBX4, NKX2-1, STAT3, TAL1, TP63, FOS, CDK8, MED1, CEBPG, CEBPB, ZNF141, TEAD1, CEBPD, KLF6, KDM5B, TP53, NFKB1, MYOD1, ELF3, JUN, TCF12, SP1, EP300, CTCF, EHF, AR, T, SOX4, YAP1, BRD4, SMC1, TEAD4

Target gene symbol (double-evidenced CRMs): DYRK1A,VPS26C,KCNJ6,TTC3,HLCS

Function elements

Human SNPs: .

Number of somatic mutations (coding): 10

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000159267, ENSG00000182670, ENSG00000157538, ENSG00000157540, ENSG00000157542,

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Deatailed information for cohesin site CDBP00418964