- Basic information
- CohesinDB ID: CDBP00418966
- Locus: chr21-37682721-37683272
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Data sourse: GSE206145-NatGen2015, GSE67783, GSE86191
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Cell type: Fibroblast, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: Mau2,SA1,Rad21,SA2
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
95% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 42%,
"14_ReprPCWk": 30%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: ZNF283, NANOG, CHD8, BRD1, CEBPA, MYCN, EBF1, RBBP5, KDM4C, ZFX, STAG2, SOX2, SOX13, DUX4, WT1, FOXA1, CBX8, ERG3, ZBTB33, TBP, PRDM10, KDM1A, YY1, RELA, ATF3, RUNX2, MYC, SMARCA4, BMI1, ONECUT1, RAD21, CHD7, ZFP36, POU5F1, SOX11, ATF4, RXRA, ATF2, ARNT, MGA, MAX, ZNF10, ZNF143, CDK8, MITF, MED1, CBX2, CEBPG, CEBPB, TRIM28, ZNF573, SCRT2, NR2F1, NEUROG2, EZH2, L3MBTL2, MYOD1, ZFP91, CTCF, JUN, SP1, GSPT2, HNF4A, SOX4, REST, TRIM24, POU2F3, ATF7, RNF2, ZNF548, BRD4, SCRT1, JUND, MAZ, ZNF175, ATF1, STAG1
- Target gene symbol (double-evidenced CRMs): KCNJ6,PSMG1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 6
- Number of somatic mutations (non-coding): 0
- Related genes and loops