- Basic information
- CohesinDB ID: CDBP00418977
- Locus: chr21-37717255-37717999
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Data sourse: ENCSR000BLD, GSE72082, ENCSR000FAD, ENCSR000EGW, GSE105028, GSE103477, GSE131606, GSE25021, GSE108869, GSE143937, ENCSR000BKV, GSE86191, GSE138405, GSE206145-NatGen2015, ENCSR000BLS, GSE206145, ENCSR000ECE, ENCSR000EDE, ENCSR153HNT, GSE126990, GSE50893
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Cell type: MCF-7, H1-hESC, RPE, Fibroblast, HCT-116, Hela-Kyoto, Hep-G2, GM2610, DKO, HeLa-S3, K-562, THP-1, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 8% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.856
- Subunit: SA1,Rad21,SMC1,SA2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
95% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 49%,
"14_ReprPCWk": 42%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: POU2F2, CHD8, SMC1A, ZSCAN5D, ZFX, XBP1, ZBTB48, WT1, DUX4, FOXA1, SRF, ERG3, ERG2, ZFHX2, RELA, MYC, RAD21, SP140, GRHL3, HIF1A, ZNF143, ZNF141, EZH2, OCA2, GRHL2, EGR2, CTCF, BCL11A, SPI1, AR, NOTCH3, MAZ, SMC3, STAG1
- Target gene symbol (double-evidenced CRMs): KCNJ6,PSMG1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 26
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000157542,
ENSG00000183527,
- Related loop:
chr21:37165903-37167741~~chr21:37711396-37713035,
chr21:37700000-37725000~~chr21:37825000-37850000,
chr21:37700000-37725000~~chr21:37875000-37900000,
chr21:37700000-37725000~~chr21:37900000-37925000,
chr21:37700000-37725000~~chr21:37925000-37950000,
chr21:37700000-37725000~~chr21:37950000-37975000,
chr21:37700000-37725000~~chr21:38050000-38075000,
chr21:37700000-37725000~~chr21:38100000-38125000,
chr21:37700000-37725000~~chr21:38125000-38150000,
chr21:37700000-37725000~~chr21:38150000-38175000,
chr21:37700000-37725000~~chr21:38325000-38350000,
chr21:37700000-37725000~~chr21:38350000-38375000,
chr21:37700000-37725000~~chr21:39125000-39150000,
chr21:37700000-37725000~~chr21:39150000-39175000,
chr21:37710058-37714050~~chr21:37769665-37771313,
chr21:37710058-37714050~~chr21:37915593-37917649,
chr21:37710058-37714050~~chr21:37917683-37919463,
chr21:37710058-37714050~~chr21:38139516-38141430,
chr21:37710487-37712977~~chr21:37915309-37917693,
chr21:37710487-37712977~~chr21:38125804-38127970,
chr21:37710487-37712977~~chr21:38355104-38357300,
chr21:37710499-37712987~~chr21:38125763-38127934,
chr21:37710638-37713716~~chr21:37914870-37917976,
chr21:37710638-37713716~~chr21:38125790-38127981,
chr21:37710736-37713758~~chr21:37914851-37917797,
chr21:37710736-37713758~~chr21:38125761-38128067,
chr21:37710736-37713758~~chr21:38169391-38172834,
chr21:37710736-37713758~~chr21:38355287-38357113,
chr21:37711372-37713046~~chr21:37915606-37917528,
chr21:37711372-37713046~~chr21:38125725-38127860,
chr21:37711375-37712997~~chr21:38217749-38220501,
chr21:37711375-37712997~~chr21:38355275-38357287,
chr21:37711392-37713025~~chr21:38125767-38127866,
chr21:37711392-37713166~~chr21:37915411-37917551,
chr21:37711392-37713166~~chr21:38125754-38127987,
chr21:37711394-37712982~~chr21:37915529-37918394,
chr21:37711394-37712982~~chr21:38125749-38127915,
chr21:37711394-37712982~~chr21:38351543-38353716,
chr21:37711394-37712982~~chr21:38355432-38357106,
chr21:37711395-37713012~~chr21:37914884-37917576,
chr21:37711395-37713012~~chr21:38125801-38127928,
chr21:37711395-37713012~~chr21:38355322-38357346,
chr21:37711396-37712996~~chr21:38125971-38127690,
chr21:37711396-37712996~~chr21:38355129-38357200,
chr21:37711396-37713035~~chr21:37915225-37917656,
chr21:37711397-37713457~~chr21:37915637-37917611,
chr21:37711397-37713457~~chr21:38125740-38127873,
chr21:37711397-37713457~~chr21:38355442-38357264,
chr21:37711406-37712950~~chr21:38125771-38127931,
chr21:37711406-37712996~~chr21:38351825-38353553,
chr21:37711406-37712996~~chr21:38355277-38357273,
chr21:37711408-37712950~~chr21:38125778-38127949,
chr21:37711418-37712993~~chr21:37915255-37918377,
chr21:37711418-37712993~~chr21:38125791-38127926,
chr21:37711434-37712961~~chr21:38126151-38127594,
chr21:37711434-37712993~~chr21:38125779-38127911,
chr21:37711438-37713000~~chr21:38125779-38127948,
chr21:37711438-37713000~~chr21:38351755-38353771,
chr21:37711438-37713000~~chr21:38355274-38357174,
chr21:37711441-37713006~~chr21:38125941-38127948,
chr21:37711441-37713006~~chr21:38355373-38357156,
chr21:37711442-37712977~~chr21:38126150-38127604,
chr21:37711445-37712965~~chr21:37915589-37917624,
chr21:37711445-37712965~~chr21:38125778-38127688,
chr21:37711446-37713025~~chr21:38125798-38127942,
chr21:37711455-37712980~~chr21:38125790-38127976,
chr21:37711455-37712980~~chr21:38351797-38353501,
chr21:37711455-37712980~~chr21:38355282-38357170,
chr21:37711458-37712951~~chr21:38355303-38357092,
chr21:37711462-37712982~~chr21:37915731-37917102,
chr21:37711462-37712982~~chr21:38126125-38127630,
chr21:37711462-37712982~~chr21:38355333-38356894,
chr21:37711467-37712985~~chr21:38125934-38127923,
chr21:37711467-37712985~~chr21:38355325-38357124,
chr21:37711477-37713059~~chr21:38351760-38353699,
chr21:37711511-37712978~~chr21:38351792-38353520,
chr21:37711568-37712969~~chr21:37915343-37917688,
chr21:37711568-37712969~~chr21:38355272-38357307,
chr21:37711574-37712971~~chr21:38126041-38127628,
chr21:37711651-37712969~~chr21:38126216-38127622,
chr21:37711651-37712969~~chr21:38355362-38356894,
chr21:37711676-37712970~~chr21:38355460-38356861,
chr21:37716838-37718336~~chr21:37915589-37917624,
chr21:37717141-37718351~~chr21:38125790-38127976,
chr21:37717141-37718351~~chr21:38351797-38353501,