- Basic information
- CohesinDB ID: CDBP00418979
- Locus: chr21-37720614-37721055
-
Data sourse: GSE206145, GSE206145-NatGen2015, GSE67783, GSE86191
-
Cell type: RPE, Fibroblast, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,Rad21,SA2
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
95% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
-
Chromatin annotation:
"15_Quies": 50%,
"14_ReprPCWk": 46%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: TOP2A, EZH2, XBP1, MAZ, CTCF
- Target gene symbol (double-evidenced CRMs): KCNJ6,PSMG1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 4
- Number of somatic mutations (non-coding): 2
- Related genes and loops
- Related gene:
ENSG00000157542,
ENSG00000183527,
- Related loop:
chr21:37700000-37725000~~chr21:37825000-37850000,
chr21:37700000-37725000~~chr21:37875000-37900000,
chr21:37700000-37725000~~chr21:37900000-37925000,
chr21:37700000-37725000~~chr21:37925000-37950000,
chr21:37700000-37725000~~chr21:37950000-37975000,
chr21:37700000-37725000~~chr21:38050000-38075000,
chr21:37700000-37725000~~chr21:38100000-38125000,
chr21:37700000-37725000~~chr21:38125000-38150000,
chr21:37700000-37725000~~chr21:38150000-38175000,
chr21:37700000-37725000~~chr21:38325000-38350000,
chr21:37700000-37725000~~chr21:38350000-38375000,
chr21:37700000-37725000~~chr21:39125000-39150000,
chr21:37700000-37725000~~chr21:39150000-39175000,
chr21:37716838-37718336~~chr21:37915589-37917624,
chr21:37717141-37718351~~chr21:38125790-38127976,
chr21:37717141-37718351~~chr21:38351797-38353501,
chr21:37725000-37750000~~chr21:37875000-37900000,
chr21:37725000-37750000~~chr21:37900000-37925000,
chr21:37725000-37750000~~chr21:37950000-37975000,
chr21:37725000-37750000~~chr21:38050000-38075000,
chr21:37725000-37750000~~chr21:38075000-38100000,
chr21:37725000-37750000~~chr21:38125000-38150000,
chr21:37725000-37750000~~chr21:38300000-38325000,
chr21:37725000-37750000~~chr21:38325000-38350000,
chr21:37725000-37750000~~chr21:38350000-38375000,
chr21:37725000-37750000~~chr21:38375000-38400000,
chr21:37725000-37750000~~chr21:38700000-38725000,