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Basic information

CohesinDB ID: CDBP00418985

Locus: chr21-37749181-37749550

Data sourse: GSE86191, GSE111913, GSE67783, GSE68388

Cell type: RT-112, HCT-116, HSPC, HuCC-T1

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 2% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.956

Subunit: SA1,Rad21,SA2,SMC1

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 95% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 51%, "14_ReprPCWk": 34%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, ZNF283, SMC1A, BRD1, ZSCAN5D, ZFX, SMAD3, ZBTB48, WT1, FOXA1, SRF, ERG3, ZNF823, HOXB13, TBP, YY1, RELA, ASCL1, NEUROD1, ETS1, RUNX2, RAD21, GRHL3, OTX2, GABPA, STAT3, TP63, IKZF1, ZNF750, MYOG, NR3C1, KLF4, KMT2A, SCRT2, EZH2, KDM5B, ESR1, TP53, TBX5, CTCF, SPI1, EHF, PAX3-FOXO1, AR, ZBTB42, POU2F3, HSF1, NCOR1, HNRNPLL, SCRT1, BRD4, TCF3, MAZ, SMC3, STAG1, TFAP2C

Target gene symbol (double-evidenced CRMs): ERG,KCNJ6,KCNJ15

Function elements

Human SNPs: .

Number of somatic mutations (coding): 6

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000157542, ENSG00000157551, ENSG00000157554,

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Deatailed information for cohesin site CDBP00418985