- Basic information
- CohesinDB ID: CDBP00418986
- Locus: chr21-37752967-37753612
-
Data sourse: GSE206145-NatGen2015, GSE67783, GSE86191
-
Cell type: Fibroblast, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21,SA2
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
68% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 41%,
"14_ReprPCWk": 35%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, EZH2phosphoT487, CHD8, ZSCAN5D, ZNF263, MYCN, NKX2-2, SOX13, ZFX, FOXA2, XBP1, SOX2, MAFF, ZBTB48, WT1, FOXA1, FOXF1, TET2, ARID3A, HNF4G, ERG, PAX6, RELA, ZNF384, USP7, ETS1, RUNX2, AHR, GATA4, SMARCA4, SP140, GRHL3, HIF1A, ARNT, MAX, MAFB, NKX3-1, ZNF143, GATA1, MITF, XRCC5, HAND2, MED1, CDX2, NR3C1, PDX1, TEAD3, TEAD1, NCOA3, CREB1, NEUROG2, ETV1, EZH2, ESR1, OCA2, TBX5, T, CTCF, USF1, SPI1, HNF4A, PAX3-FOXO1, SOX5, AR, HDAC2, YAP1, E2F6, ASH2L, BRD4, CLOCK, MAZ, NFIL3, GATAD2A, STAG1, RBPJ
- Target gene symbol (double-evidenced CRMs): KCNJ6
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 10
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000157542,
- Related loop:
chr21:37725000-37750000~~chr21:37875000-37900000,
chr21:37725000-37750000~~chr21:37900000-37925000,
chr21:37725000-37750000~~chr21:37950000-37975000,
chr21:37725000-37750000~~chr21:38050000-38075000,
chr21:37725000-37750000~~chr21:38075000-38100000,
chr21:37725000-37750000~~chr21:38125000-38150000,
chr21:37725000-37750000~~chr21:38300000-38325000,
chr21:37725000-37750000~~chr21:38325000-38350000,
chr21:37725000-37750000~~chr21:38350000-38375000,
chr21:37725000-37750000~~chr21:38375000-38400000,
chr21:37725000-37750000~~chr21:38700000-38725000,
chr21:37750000-37775000~~chr21:37875000-37900000,
chr21:37750000-37775000~~chr21:37900000-37925000,
chr21:37750000-37775000~~chr21:38025000-38050000,
chr21:37750000-37775000~~chr21:38100000-38125000,
chr21:37750000-37775000~~chr21:38125000-38150000,
chr21:37750000-37775000~~chr21:38150000-38175000,
chr21:37750000-37775000~~chr21:38350000-38375000,
chr21:37757478-37760684~~chr21:37872980-37874819,
chr21:37757478-37760684~~chr21:37914851-37917797,
chr21:37757478-37760684~~chr21:38125761-38128067,
chr21:37757478-37760684~~chr21:38355287-38357113,
chr21:37758041-37760564~~chr21:37914870-37917976,
chr21:37758041-37760564~~chr21:38125790-38127981,
chr21:37758041-37760564~~chr21:38351388-38354007,
chr21:37758054-37760218~~chr21:38125818-38127945,
chr21:37758054-37760218~~chr21:38355149-38357340,
chr21:37758083-37760394~~chr21:38120483-38122671,
chr21:37758083-37760394~~chr21:38125791-38127988,
chr21:37758083-37760394~~chr21:38355275-38357287,
chr21:37758088-37760278~~chr21:37915411-37917551,
chr21:37758088-37760278~~chr21:38125754-38127987,
chr21:37758096-37760150~~chr21:38351797-38353501,
chr21:37758111-37760132~~chr21:37915589-37917624,
chr21:37758111-37760132~~chr21:38125778-38127688,
chr21:37758111-37760132~~chr21:38355258-38357082,
chr21:37758115-37760170~~chr21:38120552-38122290,
chr21:37758115-37760170~~chr21:38125779-38127948,
chr21:37758115-37760184~~chr21:37915273-37917670,
chr21:37758129-37760281~~chr21:37915255-37918377,
chr21:37758129-37760281~~chr21:38125791-38127926,
chr21:37758130-37760186~~chr21:37915343-37917688,
chr21:37758130-37760186~~chr21:38126066-38127958,
chr21:37758130-37760186~~chr21:38351811-38353488,
chr21:37758130-37760186~~chr21:38355272-38357307,
chr21:37758135-37760096~~chr21:37915636-37917622,
chr21:37758140-37760150~~chr21:37915315-37917747,
chr21:37758140-37760150~~chr21:38125798-38127942,
chr21:37758144-37760203~~chr21:37915295-37918332,
chr21:37758144-37760203~~chr21:38125941-38127948,
chr21:37758163-37760055~~chr21:38125763-38127934,
chr21:37758163-37760055~~chr21:38351823-38353474,
chr21:37758163-37760055~~chr21:38355110-38357173,
chr21:37758198-37760138~~chr21:37914884-37917576,
chr21:37758198-37760138~~chr21:38125801-38127928,
chr21:37758212-37760210~~chr21:37915283-37917809,
chr21:37758212-37760210~~chr21:38125779-38127911,
chr21:37758230-37760229~~chr21:37915529-37918394,
chr21:37758230-37760229~~chr21:38125749-38127915,
chr21:37758320-37760162~~chr21:37915283-37917707,
chr21:37758324-37760023~~chr21:37915309-37917693,
chr21:37758324-37760023~~chr21:38125804-38127970,
chr21:37758368-37760158~~chr21:37915292-37917676,
chr21:37758368-37760158~~chr21:38125770-38127709,
chr21:37758370-37760095~~chr21:38125971-38127690,
chr21:37758391-37760172~~chr21:38126009-38127637,
chr21:37758392-37760187~~chr21:38355277-38357273,
chr21:37758409-37759787~~chr21:37915637-37917611,
chr21:37758410-37759974~~chr21:38125958-38127687,
chr21:37758410-37760220~~chr21:38355384-38357279,
chr21:37758419-37759941~~chr21:38125927-38127658,
chr21:37758428-37759911~~chr21:38125778-38127949,
chr21:37758446-37759976~~chr21:38125725-38127860,
chr21:37758468-37759930~~chr21:38126131-38127619,
chr21:37758479-37759910~~chr21:38126125-38127630,
chr21:37758504-37759946~~chr21:38355473-38356966,
chr21:37758513-37759885~~chr21:38126191-38127689,
chr21:37758520-37759866~~chr21:38126208-38127589,
chr21:37758520-37759927~~chr21:38352107-38353483,
chr21:37758533-37759896~~chr21:38169685-38171409,
chr21:37758563-37759871~~chr21:38126251-38127506,