- Basic information
- CohesinDB ID: CDBP00418990
- Locus: chr21-37765099-37765707
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Data sourse: GSE85526, GSE206145-GSE177045
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Cell type: MCF-7, HEKn
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: Mau2,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
68% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 52%,
"14_ReprPCWk": 27%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: SMC1A, FOXA2, SIN3A, NFATC1, MTA2, SMAD3, FOXA1, HOXB13, TFAP4, KDM1A, RELA, MEF2A, JUNB, NFIC, RAD21, GATA3, ATF2, BATF, SMARCE1, STAT3, TP63, FOS, IKZF1, RCOR1, NR3C1, ESRRA, ZNF750, CEBPB, TEAD1, TFAP2C, PIAS1, TCF7L2, NEUROG2, TP53, ESR1, PKNOX1, GRHL2, PHOX2B, JUN, BAF155, SPI1, EHF, AR, DPF2, HDAC2, POU2F3, CTBP2, MBD2, CUX1, E2F1, AHR
- Target gene symbol (double-evidenced CRMs): KCNJ6
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 4
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000157542,
- Related loop:
chr21:37710058-37714050~~chr21:37769665-37771313,
chr21:37750000-37775000~~chr21:37875000-37900000,
chr21:37750000-37775000~~chr21:37900000-37925000,
chr21:37750000-37775000~~chr21:38025000-38050000,
chr21:37750000-37775000~~chr21:38100000-38125000,
chr21:37750000-37775000~~chr21:38125000-38150000,
chr21:37750000-37775000~~chr21:38150000-38175000,
chr21:37750000-37775000~~chr21:38350000-38375000,
chr21:37757478-37760684~~chr21:37872980-37874819,
chr21:37757478-37760684~~chr21:37914851-37917797,
chr21:37757478-37760684~~chr21:38125761-38128067,
chr21:37757478-37760684~~chr21:38355287-38357113,
chr21:37758041-37760564~~chr21:37914870-37917976,
chr21:37758041-37760564~~chr21:38125790-38127981,
chr21:37758041-37760564~~chr21:38351388-38354007,
chr21:37758054-37760218~~chr21:38125818-38127945,
chr21:37758054-37760218~~chr21:38355149-38357340,
chr21:37758083-37760394~~chr21:38120483-38122671,
chr21:37758083-37760394~~chr21:38125791-38127988,
chr21:37758083-37760394~~chr21:38355275-38357287,
chr21:37758088-37760278~~chr21:37915411-37917551,
chr21:37758088-37760278~~chr21:38125754-38127987,
chr21:37758096-37760150~~chr21:38351797-38353501,
chr21:37758111-37760132~~chr21:37915589-37917624,
chr21:37758111-37760132~~chr21:38125778-38127688,
chr21:37758111-37760132~~chr21:38355258-38357082,
chr21:37758115-37760170~~chr21:38120552-38122290,
chr21:37758115-37760170~~chr21:38125779-38127948,
chr21:37758115-37760184~~chr21:37915273-37917670,
chr21:37758129-37760281~~chr21:37915255-37918377,
chr21:37758129-37760281~~chr21:38125791-38127926,
chr21:37758130-37760186~~chr21:37915343-37917688,
chr21:37758130-37760186~~chr21:38126066-38127958,
chr21:37758130-37760186~~chr21:38351811-38353488,
chr21:37758130-37760186~~chr21:38355272-38357307,
chr21:37758140-37760150~~chr21:37915315-37917747,
chr21:37758140-37760150~~chr21:38125798-38127942,
chr21:37758144-37760203~~chr21:37915295-37918332,
chr21:37758144-37760203~~chr21:38125941-38127948,
chr21:37758198-37760138~~chr21:37914884-37917576,
chr21:37758198-37760138~~chr21:38125801-38127928,
chr21:37758212-37760210~~chr21:37915283-37917809,
chr21:37758212-37760210~~chr21:38125779-38127911,
chr21:37758230-37760229~~chr21:37915529-37918394,
chr21:37758230-37760229~~chr21:38125749-38127915,
chr21:37758320-37760162~~chr21:37915283-37917707,
chr21:37758368-37760158~~chr21:37915292-37917676,
chr21:37758368-37760158~~chr21:38125770-38127709,
chr21:37758391-37760172~~chr21:38126009-38127637,
chr21:37758392-37760187~~chr21:38355277-38357273,
chr21:37758410-37760220~~chr21:38355384-38357279,