- Basic information
- CohesinDB ID: CDBP00418993
- Locus: chr21-37771853-37772380
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Data sourse: GSE206145-NatGen2015
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Cell type: Fibroblast
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.989
- Subunit: Mau2
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
68% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 66%,
"14_ReprPCWk": 26%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: NANOG, FOXA2, MYCN, ZNF660, ZNF335, ZNF317, GTF2B, DUX4, FOXA1, ZNF563, ERG3, HOXB13, ZFHX2, PRDM10, ZBTB21, RELA, JUNB, ATF3, NEUROD1, EOMES, GATA4, CHD7, RAD21, GRHL3, OTX2, GATA3, ZNF518A, STAT3, MAX, GATA1, FOS, ZNF667, HAND2, DACH1, CEBPB, SCRT2, NEUROG2, ESR1, EBF3, EGR2, PHOX2B, CTCF, GATA6, FLI1, JUND, ZNF418, TBX2
- Target gene symbol (double-evidenced CRMs): KCNJ6
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 16
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000157542,
- Related loop:
chr21:37710058-37714050~~chr21:37769665-37771313,
chr21:37750000-37775000~~chr21:37875000-37900000,
chr21:37750000-37775000~~chr21:37900000-37925000,
chr21:37750000-37775000~~chr21:38025000-38050000,
chr21:37750000-37775000~~chr21:38100000-38125000,
chr21:37750000-37775000~~chr21:38125000-38150000,
chr21:37750000-37775000~~chr21:38150000-38175000,
chr21:37750000-37775000~~chr21:38350000-38375000,
chr21:37775000-37800000~~chr21:37875000-37900000,
chr21:37775000-37800000~~chr21:37900000-37925000,