- Basic information
- CohesinDB ID: CDBP00419001
- Locus: chr21-37801202-37801706
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Data sourse: GSE206145-NatGen2015, GSE67783, GSE86191
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Cell type: Fibroblast, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21,SA2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
68% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 58%,
"14_ReprPCWk": 30%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, GLIS1, PGR, CHD8, PPARG, EZH2phosphoT487, LDB1, MEIS1, MYCN, ZFX, SOX2, XBP1, SMAD3, ESR2, FOXA1, FOXF1, STAT1, CBX8, SUZ12, PBX2, TFAP4, ERG, RELA, LYL1, RUNX2, MYC, GATA4, CHD7, PRDM1, ARNT, MAF1, STAT3, TAL1, NRIP1, FOS, CDK8, GATA1, CBFA2T3, ZNF143, NR3C1, CEBPB, TRIM28, ETV1, TCF7L2, EZH2, LMO2, ESR1, STAG1, EBF3, CTCF, TCF12, BCL11A, AR, GATA6, GATA2, E2F6, NOTCH3, BRD4, TCF3, PDX1, TFAP2C
- Target gene symbol (double-evidenced CRMs): ERG,KCNJ6
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 14
- Number of somatic mutations (non-coding): 0
- Related genes and loops