- Basic information
- CohesinDB ID: CDBP00419012
- Locus: chr21-37841983-37843096
-
Data sourse: ENCSR230ZWH, GSE67783, GSE86191, ENCSR153HNT, ENCSR917QNE
-
Cell type: K-562, Liver, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,Rad21
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
68% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 50%,
"14_ReprPCWk": 19%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: CHD8, FOXA2, NKX2-2, SIRT6, MYCN, ZNF263, ZFX, POU4F2, ZNF317, XBP1, WT1, ZSCAN5D, TOP2A, FOXA1, SS18, ZBTB33, ERG, YY1, RELA, ATF3, ONECUT1, RUNX2, CHD7, GRHL3, HIF1A, RXRA, ATF2, ZNF189, NKX3-1, ZNF143, CDK8, ZNF736, NR3C1, CEBPB, MYOG, ZNF586, NCOA3, SCRT2, CREB1, EZH2, STAG1, ESR1, ZNF547, GRHL2, ZNF334, SETDB1, TBX5, CTCF, MAFK, SP1, SPI1, GSPT2, HNF4A, AR, PAX3-FOXO1, NKX2-5, GATA2, EGR1, NOTCH3, JUND, FOXP1, SMC3, PDX1
- Target gene symbol (double-evidenced CRMs): KCNJ6
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 18
- Number of somatic mutations (non-coding): 0
- Related genes and loops