- Basic information
- CohesinDB ID: CDBP00419019
- Locus: chr21-37862475-37863023
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Data sourse: ENCSR000BLD, ENCSR230ZWH, GSE68388, GSE108869, ENCSR917QNE
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Cell type: Liver, H1-hESC, HeLa-S3, HuCC-T1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: Rad21,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
68% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 68%,
"7_Enh": 14%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, FOXO1, SKI, GLIS1, CBFA2T2, CIITA, FOXA2, NKX2-2, EBF1, LDB1, CEBPA, ZFX, TEAD4, CREM, MYCN, WT1, FOXA1, SUZ12, PBX2, YY1, RELA, IRF2, ASCL1, NEUROD1, MYC, RUNX2, GATA4, RAD21, BRCA1, ARNT, GRHL3, HIF1A, RXRA, OTX2, GATA3, ATF2, TAL1, MAX, MAFB, NKX3-1, ZNF143, CDK8, NFE2, HAND2, MED1, CEBPB, ELF1, TRIM28, KMT2A, MYB, NEUROG2, CREB1, LMO2, ESR1, PKNOX1, ZFP42, ZNF41, GRHL2, MYOD1, CTCF, ELF3, ZHX2, SP1, SPI1, BCL11A, LMO1, HNF4A, AR, GATA2, RFX5, ATF7, ZNF548, BRD4, JUND, TCF3, FOXP1, E2F1, MAZ, BCOR, SMC3, ATF1, PDX1, AHR
- Target gene symbol (double-evidenced CRMs): KCNJ6,BRWD1,VPS26C,PSMG1,HLCS,ETS2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 6
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000159267,
ENSG00000157538,
ENSG00000157542,
ENSG00000157557,
ENSG00000183527,
ENSG00000185658,
- Related loop:
chr21:36975000-37000000~~chr21:37850000-37875000,
chr21:37250000-37275000~~chr21:37850000-37875000,
chr21:37850000-37875000~~chr21:37950000-37975000,
chr21:37850000-37875000~~chr21:38325000-38350000,
chr21:37850000-37875000~~chr21:38775000-38800000,
chr21:37850000-37875000~~chr21:38800000-38825000,
chr21:37850000-37875000~~chr21:39175000-39200000,