- Basic information
- CohesinDB ID: CDBP00419024
- Locus: chr21-37873511-37874441
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Data sourse: ENCSR000BLD, GSE206145-GSE177045, ENCSR230ZWH, GSE72082, ENCSR501LQA, ENCSR000EGW, ENCSR000BLY, GSE105028, GSE131606, ENCSR330ELC, GSE108869, GSE25021, ENCSR917QNE, ENCSR000EFJ, ENCSR000BTU, ENCSR000BKV, GSE138405, GSE76893, GSE101921, GSE135093, GSE51234, GSE206145-NatGen2015, ENCSR199XBQ, ENCSR703TNG, GSE116344, GSE145327, ENCSR768DOX, ENCSR000BLS, GSE206145, ENCSR000ECE, ENCSR247LSH, ENCSR981FDC, ENCSR620NWG, ENCSR767DFK, GSE97394, ENCSR217ELF, ENCSR000BTQ, GSE105004, ENCSR167MTG, ENCSR853VWZ, ENCSR956LGB, ENCSR944ZCT, GSE110061, ENCSR000HPG, ENCSR335RKQ, ENCSR054FKH, ENCSR000EDE, GSE68388, GSE126990, GSE126755, ENCSR000ECS
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Cell type: RH4, Liver, GP5d, HuCC-T1, H9-hESC, RPE, HMEC, Fibroblast, Ishikawa, HeLa-S3, IMR-90, K-562, DKO, H1-hESC, SK-N-SH, HUES64, MCF-7, Hela-Kyoto, HCT-116, Hep-G2, A-549, HCAEC, HeLa, Neutrophil
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 19% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.733
- Subunit: SA1,Rad21,SMC1,SA2,SMC3
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CTCF binding site: CTCF
CTCF motif: True
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
68% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 51%,
"14_ReprPCWk": 28%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RELA, GRHL3
- Target gene symbol (double-evidenced CRMs): HLCS,PSMG1,KCNJ6,ETS2,VPS26C,BRWD1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 8
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000159267,
ENSG00000157538,
ENSG00000157542,
ENSG00000157557,
ENSG00000183527,
ENSG00000185658,
- Related loop:
chr21:36975000-37000000~~chr21:37850000-37875000,
chr21:37250000-37275000~~chr21:37850000-37875000,
chr21:37700000-37725000~~chr21:37875000-37900000,
chr21:37725000-37750000~~chr21:37875000-37900000,
chr21:37750000-37775000~~chr21:37875000-37900000,
chr21:37757478-37760684~~chr21:37872980-37874819,
chr21:37775000-37800000~~chr21:37875000-37900000,
chr21:37850000-37875000~~chr21:37950000-37975000,
chr21:37850000-37875000~~chr21:38325000-38350000,
chr21:37850000-37875000~~chr21:38775000-38800000,
chr21:37850000-37875000~~chr21:38800000-38825000,
chr21:37850000-37875000~~chr21:39175000-39200000,
chr21:37873271-37874436~~chr21:38355282-38357170,
chr21:37875000-37900000~~chr21:38350000-38375000,