- Basic information
- CohesinDB ID: CDBP00419026
- Locus: chr21-37876665-37877767
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Data sourse: ENCSR000EFJ, GSE206145-GSE177045, ENCSR217ELF, GSE68388, ENCSR767DFK, ENCSR748MVX, GSE165895
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Cell type: MCF-7, A-549, IMR-90, HuCC-T1, HFFc6
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: Mau2,SMC3,Rad21,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
68% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 44%,
"14_ReprPCWk": 28%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: PGR, NKX2-2, DUX4, SMAD3, FOXA1, ERG3, HOXB13, PRDM10, ERG, RELA, NRF1, GATA3, PRDM9, MED1, NR3C1, CEBPB, KLF4, ESRRA, TEAD1, NR2F2, TFAP2C, KDM5B, ESR1, TP53, GRHL2, NFKB1, JUN, ZHX2, BAF155, AR, ZNF257, HDAC2, GATA2, ASH2L, HSF1, BRD4, TEAD4, AHR
- Target gene symbol (double-evidenced CRMs): KCNJ6
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 10
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000157542,
- Related loop:
chr21:36975000-37000000~~chr21:37850000-37875000,
chr21:37250000-37275000~~chr21:37850000-37875000,
chr21:37700000-37725000~~chr21:37875000-37900000,
chr21:37725000-37750000~~chr21:37875000-37900000,
chr21:37750000-37775000~~chr21:37875000-37900000,
chr21:37757478-37760684~~chr21:37872980-37874819,
chr21:37775000-37800000~~chr21:37875000-37900000,
chr21:37850000-37875000~~chr21:37950000-37975000,
chr21:37850000-37875000~~chr21:38325000-38350000,
chr21:37850000-37875000~~chr21:38775000-38800000,
chr21:37850000-37875000~~chr21:38800000-38825000,
chr21:37850000-37875000~~chr21:39175000-39200000,
chr21:37873271-37874436~~chr21:38355282-38357170,
chr21:37875000-37900000~~chr21:38350000-38375000,