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Basic information

CohesinDB ID: CDBP00419035

Locus: chr21-37896452-37897729

Data sourse: GSE67783, GSE86191, GSE206145-NatGen2015, ENCSR153HNT, GSE68388

Cell type: Fibroblast, HCT-116, K-562, HSPC, HuCC-T1

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.944

Subunit: SA1,Rad21,SMC1

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 68% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "14_ReprPCWk": 39%, "15_Quies": 35%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: GLIS1, POU2F2, SMC1A, PGR, AGO1, MYCN, RUNX1T1, ZNF335, ZFX, TOP2A, XBP1, ZBTB48, ZSCAN5A, WT1, FOXA1, TET2, SUZ12, HOXB13, ERG, YY1, RELA, CREBBP, ZNF384, ASCL1, RUNX2, CDK6, SP140, ARNT, HIF1A, GRHL3, MAX, ZNF143, NFE2, NR3C1, CREB1, NEUROG2, PIAS1, EZH2, KDM5B, ESR1, GRHL2, CTCF, JUN, MAFK, BAF155, AR, GATA6, HDAC2, GATA2, EGLN2, HEXIM1, FLI1, RNF2, BRD4, MAZ, SMC3, STAG1, ZNF316

Target gene symbol (double-evidenced CRMs): KCNJ6

Function elements

Human SNPs: .

Number of somatic mutations (coding): 12

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000157542,

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Deatailed information for cohesin site CDBP00419035