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Basic information

CohesinDB ID: CDBP00419038

Locus: chr21-37909892-37910463

Data sourse: ENCSR000BLD, GSE72082, ENCSR000FAD, ENCSR760NPX, ENCSR000BLY, GSE105028, GSE131606, GSE108869, GSE25021, ENCSR000BKV, GSE138405, ENCSR703TNG, ENCSR895JMI, ENCSR000BLS, ENCSR000ECE, ENCSR247LSH, ENCSR807WAC, GSE97394, ENCSR217ELF, ENCSR000BTQ, ENCSR853VWZ, ENCSR944ZCT, ENCSR000EDE, ENCSR153HNT, GSE68388, GSE126990, ENCSR748MVX

Cell type: MCF-7, H1-hESC, Hela-Kyoto, Hep-G2, A-549, DKO, HeLa-S3, HUES64, SK-N-SH, K-562, HuCC-T1, H9-hESC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 10% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.867

Subunit: SA1,Rad21,SMC1,SA2,SMC3

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 68% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "14_ReprPCWk": 63%, "15_Quies": 24%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RELA, CEBPA, SCRT2, ZFX, RAD21, ZBTB26, ESR1, SCRT1, TAL1, HIF1A, CLOCK, GABPA, SRF, ZNF823, SMC3, CTCF, ZBTB33, ZNF143, STAG1

Target gene symbol (double-evidenced CRMs): HLCS,VPS26C,DYRK1A,KCNJ6,TTC3

Function elements

Human SNPs: .

Number of somatic mutations (coding): 4

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000159267, ENSG00000182670, ENSG00000157538, ENSG00000157540, ENSG00000157542,

eachgene

Deatailed information for cohesin site CDBP00419038