- Basic information
- CohesinDB ID: CDBP00419041
- Locus: chr21-37920872-37921888
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Data sourse: ENCSR501LQA, ENCSR760NPX, ENCSR150EFU, ENCSR330ELC, GSE206145-NatGen2015, ENCSR806UKK, ENCSR199XBQ, ENCSR895JMI, ENCSR193NSH, ENCSR768DOX, ENCSR981FDC, ENCSR247LSH, ENCSR807WAC, ENCSR620NWG, ENCSR767DFK, ENCSR495WGO, ENCSR984DZW, ENCSR217ELF, ENCSR853VWZ, ENCSR956LGB, ENCSR944ZCT, ENCSR676MJK, ENCSR335RKQ, ENCSR537EFT, GSE68388, ENCSR748MVX
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Cell type: Fibroblast, A-549, HuCC-T1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 10% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21,SMC1,SA2,SMC3
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
68% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
-
Chromatin annotation:
"14_ReprPCWk": 52%,
"15_Quies": 23%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: NANOG, SMC1A, PPARG, FOXA2, POU5F1, ZNF263, CHD8, SOX2, ZFX, POU2F2, HNF1A, XBP1, SMAD3, POU4F2, FOXA1, CHD7, GRHL3, NKX2-1, GATA3, PRDM9, FOS, MED1, NR3C1, CEBPB, TEAD1, TERF1, NR1H2, HNF1B, PHOX2B, ELF3, TCF12, JUN, SP1, SPI1, AR, NOTCH3, JUND, BRD4, TEAD4, FOSL2
- Target gene symbol (double-evidenced CRMs): TTC3,KCNJ6,VPS26C,DYRK1A,HLCS
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 5
- Number of somatic mutations (non-coding): 3
- Related genes and loops
- Related gene:
ENSG00000159267,
ENSG00000182670,
ENSG00000157538,
ENSG00000157540,
ENSG00000157542,
- Related loop:
chr21:36975000-37000000~~chr21:37900000-37925000,
chr21:36989176-36991225~~chr21:37915637-37917611,
chr21:37150000-37175000~~chr21:37900000-37925000,
chr21:37225000-37250000~~chr21:37900000-37925000,
chr21:37350000-37375000~~chr21:37900000-37925000,
chr21:37674271-37677011~~chr21:37915315-37917747,
chr21:37674744-37676208~~chr21:37915891-37917039,
chr21:37699607-37702263~~chr21:37914870-37917976,
chr21:37699764-37701688~~chr21:37915637-37917611,
chr21:37699862-37702222~~chr21:37915255-37918377,
chr21:37700000-37725000~~chr21:37900000-37925000,
chr21:37700000-37725000~~chr21:37925000-37950000,
chr21:37710058-37714050~~chr21:37915593-37917649,
chr21:37710058-37714050~~chr21:37917683-37919463,
chr21:37710487-37712977~~chr21:37915309-37917693,
chr21:37710638-37713716~~chr21:37914870-37917976,
chr21:37710736-37713758~~chr21:37914851-37917797,
chr21:37711372-37713046~~chr21:37915606-37917528,
chr21:37711392-37713166~~chr21:37915411-37917551,
chr21:37711394-37712982~~chr21:37915529-37918394,
chr21:37711395-37713012~~chr21:37914884-37917576,
chr21:37711396-37713035~~chr21:37915225-37917656,
chr21:37711397-37713457~~chr21:37915637-37917611,
chr21:37711418-37712993~~chr21:37915255-37918377,
chr21:37711445-37712965~~chr21:37915589-37917624,
chr21:37711462-37712982~~chr21:37915731-37917102,
chr21:37711568-37712969~~chr21:37915343-37917688,
chr21:37716838-37718336~~chr21:37915589-37917624,
chr21:37725000-37750000~~chr21:37900000-37925000,
chr21:37750000-37775000~~chr21:37900000-37925000,
chr21:37757478-37760684~~chr21:37914851-37917797,
chr21:37758041-37760564~~chr21:37914870-37917976,
chr21:37758088-37760278~~chr21:37915411-37917551,
chr21:37758111-37760132~~chr21:37915589-37917624,
chr21:37758115-37760184~~chr21:37915273-37917670,
chr21:37758129-37760281~~chr21:37915255-37918377,
chr21:37758130-37760186~~chr21:37915343-37917688,
chr21:37758135-37760096~~chr21:37915636-37917622,
chr21:37758140-37760150~~chr21:37915315-37917747,
chr21:37758144-37760203~~chr21:37915295-37918332,
chr21:37758198-37760138~~chr21:37914884-37917576,
chr21:37758212-37760210~~chr21:37915283-37917809,
chr21:37758230-37760229~~chr21:37915529-37918394,
chr21:37758320-37760162~~chr21:37915283-37917707,
chr21:37758324-37760023~~chr21:37915309-37917693,
chr21:37758368-37760158~~chr21:37915292-37917676,
chr21:37758409-37759787~~chr21:37915637-37917611,
chr21:37775000-37800000~~chr21:37900000-37925000,
chr21:37800000-37825000~~chr21:37900000-37925000,
chr21:37900000-37925000~~chr21:38125000-38150000,
chr21:37900000-37925000~~chr21:38150000-38175000,
chr21:37900000-37925000~~chr21:38325000-38350000,
chr21:37900000-37925000~~chr21:38350000-38375000,
chr21:37914870-37917976~~chr21:38355308-38357138,
chr21:37915283-37917809~~chr21:38125779-38127911,
chr21:37915315-37917747~~chr21:38125798-38127942,
chr21:37915343-37917688~~chr21:38126066-38127958,
chr21:37915529-37918394~~chr21:38125749-38127915,
chr21:37915529-37918394~~chr21:38355432-38357106,
chr21:37915593-37917649~~chr21:38125927-38127658,
chr21:37915609-37917622~~chr21:38125799-38127662,
chr21:37917683-37919463~~chr21:38139516-38141430,
chr21:37925000-37950000~~chr21:38025000-38050000,
chr21:37925000-37950000~~chr21:38350000-38375000,
chr21:37925000-37950000~~chr21:38525000-38550000,