- Basic information
- CohesinDB ID: CDBP00419043
- Locus: chr21-37939152-37939573
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Data sourse: GSE67783, GSE68388
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Cell type: HSPC, HuCC-T1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
68% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 63%,
"14_ReprPCWk": 21%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, PGR, CHD8, PPARG, POU5F1, MYCN, SIRT6, TOP2A, ZFX, XBP1, SMAD3, WT1, ZBTB48, FOXA1, TET2, HOXB13, TFAP4, YY1, RELA, CREBBP, ERG, HOXC5, ZNF341, ATF3, MYC, ZNF184, SP140, PBX4, HIF1A, ARNT, ATF2, MAX, NKX3-1, FOS, CDX2, TLE3, ESRRA, NR2F2, PIAS1, ZMYM3, EZH2, TP53, OCA2, NR1H2, ESR1, PHOX2B, CTCF, BAF155, EP300, AR, GATA2, RBM25, FLI1, NCOR1, JUND, FOXP1, STAG1, FOSL2
- Target gene symbol (double-evidenced CRMs): KCNJ6,ERG
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 2
- Number of somatic mutations (non-coding): 0
- Related genes and loops