- Basic information
- CohesinDB ID: CDBP00419045
- Locus: chr21-37944394-37945141
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Data sourse: ENCSR198ZYJ, ENCSR153HNT, ENCSR404BPV
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Cell type: K-562, Neurons-H1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1,Rad21,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
68% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 60%,
"14_ReprPCWk": 30%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, CHD8, ZSCAN5D, EZH2phosphoT487, EBF1, MYCN, SOX2, ZFX, ZBTB48, WT1, RELA, ASCL1, BMI1, MYC, RFX1, CHD7, ARNT, SOX11, STAT3, MAX, SMARCE1, ZNF143, MED1, NCOA3, EZH2, MYOD1, CTCF, POU2F1, BCL11A, EP300, GSPT2, REST, POU2F3, NOTCH3, BRD4, SMC3, STAG1
- Target gene symbol (double-evidenced CRMs): KCNJ6,ERG
- Function elements
- Human SNPs: Rosacea_symptom_severity
- Number of somatic mutations (coding): 9
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000157542,
ENSG00000157554,
- Related loop:
chr21:37700000-37725000~~chr21:37925000-37950000,
chr21:37700000-37725000~~chr21:37950000-37975000,
chr21:37725000-37750000~~chr21:37950000-37975000,
chr21:37825000-37850000~~chr21:37950000-37975000,
chr21:37850000-37875000~~chr21:37950000-37975000,
chr21:37925000-37950000~~chr21:38025000-38050000,
chr21:37925000-37950000~~chr21:38350000-38375000,
chr21:37925000-37950000~~chr21:38525000-38550000,
chr21:37950000-37975000~~chr21:38050000-38075000,
chr21:37950000-37975000~~chr21:38075000-38100000,
chr21:37950000-37975000~~chr21:38125000-38150000,