- Basic information
- CohesinDB ID: CDBP00419046
- Locus: chr21-37947164-37947554
-
Data sourse: GSE67783, GSE86191
-
Cell type: HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1,Rad21
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
68% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
-
Chromatin annotation:
"15_Quies": 52%,
"14_ReprPCWk": 34%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: POU2F2, CHD8, BRD1, MYCN, SOX2, ZFX, ZBTB48, ZSCAN5A, WT1, FOXA1, STAT1, DDX5, RELA, MYC, SP140, MAX, PRDM14, SUPT5H, ZNF143, NR3C1, EZH2, CTCF, MNT, AR, BRD4, MAZ, SMC3, STAG1
- Target gene symbol (double-evidenced CRMs): ERG,KCNJ6
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 3
- Number of somatic mutations (non-coding): 3
- Related genes and loops
- Related gene:
ENSG00000157542,
ENSG00000157554,
- Related loop:
chr21:37700000-37725000~~chr21:37925000-37950000,
chr21:37700000-37725000~~chr21:37950000-37975000,
chr21:37725000-37750000~~chr21:37950000-37975000,
chr21:37825000-37850000~~chr21:37950000-37975000,
chr21:37850000-37875000~~chr21:37950000-37975000,
chr21:37925000-37950000~~chr21:38025000-38050000,
chr21:37925000-37950000~~chr21:38350000-38375000,
chr21:37925000-37950000~~chr21:38525000-38550000,
chr21:37950000-37975000~~chr21:38050000-38075000,
chr21:37950000-37975000~~chr21:38075000-38100000,
chr21:37950000-37975000~~chr21:38125000-38150000,