- Basic information
- CohesinDB ID: CDBP00419051
- Locus: chr21-37965086-37965832
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Data sourse: ENCSR000BLD, GSE72082, GSE105028, GSE206145-NatGen2015, ENCSR153HNT, GSE68388, GSE83726, GSE116344, GSE25021
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Cell type: MCF-7, H1-hESC, Fibroblast, RH4, K-562, HuCC-T1, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.922
- Subunit: SA1,Rad21,SA2,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
68% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"14_ReprPCWk": 47%,
"15_Quies": 40%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: CHD8, FOXA2, SIRT6, MYCN, POU5F1, SOX2, ZFX, XBP1, ZBTB48, WT1, DUX4, TET2, CDK9, HOXB13, YY1, RELA, CTCFL, RAD21, SP140, ARNT, HIF1A, TAL1, XRCC5, MAX, CBX2, PLAG1, EZH2, ESR1, USF2, PHOX2B, CTCF, USF1, GSPT2, PAX3-FOXO1, HSF1, BRD4, FOXP1, MAZ, SMC3, STAG1
- Target gene symbol (double-evidenced CRMs): KCNJ6
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 5
- Number of somatic mutations (non-coding): 0
- Related genes and loops