- Basic information
- CohesinDB ID: CDBP00419060
- Locus: chr21-37986630-37987505
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Data sourse: GSE138405, GSE206145-GSE177045, GSE120943, GSE98367
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Cell type: MCF-7, Hela-Kyoto, Monocytes, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: Mau2,SA2,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
68% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"14_ReprPCWk": 45%,
"15_Quies": 44%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: PGR, ZSCAN5C, XBP1, FOXA1, SUZ12, PBX2, MLL4, TFAP4, ZFP64, KLF14, PAX5, MZF1, HDAC3, CDX2, KLF5, TEAD1, ZNF121, KLF10, ESR1, TCF12, BAF155, ZBTB20, ZNF423, NR5A2, ZNF528, ZNF350, KLF3, TEAD4, PDX1, TFAP2C, GLIS1, NANOG, MYCN, ZNF263, ZNF778, TOP2A, ERF, ZBTB17, ZBTB48, ZNF317, SP4, TBP, ERG, ZBTB21, ASCL1, ZBTB8A, ZNF341, MYC, SMARCA4, TSHZ1, ARID1B, RAD21, GRHL3, GABPA, STAT3, NKX3-1, ZNF398, DACH1, VDR, ESRRA, CEBPB, CREB1, EZH2, KLF8, FEZF1, SPI1, KLF17, HDAC2, GATA2, RUNX1, NKX2-2, SIN3A, ZNF335, AFF4, ZFX, SMAD3, ZNF770, ZNF18, PRDM10, CREBBP, ZNF35, RUNX2, OSR2, ARNT, NFIB, SOX11, PBX4, ATF2, ZEB2, ZNF518A, CBFA2T3, FOXM1, MAFB, CDK8, MED1, PIAS1, KLF16, BCL11A, NIPBL, OVOL3, ARID1A, ASH2L, PHIP, FOXP1, PRDM6, SMC3, NCOR2, CBFA2T2, FOXA2, ZNF692, ZSCAN16, WT1, HOXB13, ZNF580, KLF7, ZNF19, RELA, ZNF510, ZNF610, ZIC2, TCF4, GATA3, TAL1, MAX, NRIP1, GATA1, HAND2, TLE3, SP7, NR2F2, NEUROG2, TCF7L2, TP53, PKNOX1, ZNF213, PHOX2B, ZNF843, AR, ZBTB42, NCOR1, BRD4, TBX2, AHR
- Target gene symbol (double-evidenced CRMs): KCNJ6
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 11
- Number of somatic mutations (non-coding): 0
- Related genes and loops