- Basic information
- CohesinDB ID: CDBP00419063
- Locus: chr21-38014870-38015356
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Data sourse: ENCSR000BLD, ENCSR000BTQ, GSE67783, GSE72082, GSE86191, GSE76893, GSE105028, GSE68388, GSE112028, GSE83726, ENCSR703TNG, GSE25021
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Cell type: MCF-7, H1-hESC, HCT-116, RH4, HeLa-Tet-On, HSPC, HuCC-T1, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 5% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.911
- Subunit: SA1,Rad21,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
69% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 50%,
"14_ReprPCWk": 39%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: NCOA2, GLIS1, SMC1A, BRD3, EBF1, TOP2A, MYCN, ZFX, POU4F2, XBP1, SMAD3, ZBTB48, WT1, FOXA1, BAHD1, RELA, CREBBP, ATF3, SMARCA4, THAP1, RAD21, ARNT, GRHL3, STAT3, FOS, SUPT5H, NCOA3, TFAP2C, NR2F1, ZNF3, TP53, ESR1, ZNF334, JUN, CTCF, SPI1, PAX3-FOXO1, ZNF257, NOTCH3, JUND, BRD4, MAZ, SMC3, STAG1, AHR
- Target gene symbol (double-evidenced CRMs): KCNJ6
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 6
- Number of somatic mutations (non-coding): 6
- Related genes and loops