- Basic information
- CohesinDB ID: CDBP00419067
- Locus: chr21-38027786-38028401
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Data sourse: ENCSR895JMI, GSE138405, ENCSR335RKQ, ENCSR981FDC, GSE206145-NatGen2015, GSE126990, GSE165895
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Cell type: Fibroblast, A-549, Hela-Kyoto, HFFc6
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,Rad21,SMC1,SA2,Mau2,SMC3
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
69% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 50%,
"14_ReprPCWk": 40%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOSL1, PGR, CREM, SMAD3, HIC1, PBX2, ARID3A, YY2, HOXB13, ERG, ZBTB21, RELA, HDGF, JUNB, ATF3, MYC, SMARCA4, ZNF362, ZNF184, OSR2, SP3, ARID1B, GATA4, PBX4, KLF14, GABPA, ZEB2, STAT3, SMARCE1, MAX, GATA1, ZNF398, FOS, MED1, KLF4, ZNF629, SP7, ZEB1, ELF1, NR3C1, CREB1, ZNF791, ZBTB11, TP53, KLF8, NFKB1, GABPB1, KLF16, JUN, BAF155, EP300, EHF, AR, KLF17, DPF2, SOX4, GATA2, SOX6, FLI1, BRD4, JUND, E2F1, ATF1, PDX1, FOSL2
- Target gene symbol (double-evidenced CRMs): KCNJ6
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 4
- Number of somatic mutations (non-coding): 0
- Related genes and loops