- Basic information
- CohesinDB ID: CDBP00419070
- Locus: chr21-38037187-38038083
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Data sourse: ENCSR501LQA, ENCSR760NPX, ENCSR330ELC, GSE76893, ENCSR806UKK, GSE120943, ENCSR199XBQ, ENCSR895JMI, ENCSR193NSH, ENCSR768DOX, ENCSR981FDC, ENCSR247LSH, ENCSR807WAC, ENCSR620NWG, ENCSR767DFK, ENCSR495WGO, ENCSR984DZW, ENCSR217ELF, ENCSR853VWZ, ENCSR956LGB, ENCSR944ZCT, ENCSR676MJK, ENCSR335RKQ, ENCSR537EFT, GSE68388, ENCSR748MVX
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Cell type: A-549, Monocytes, HuCC-T1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 9% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SMC3,Rad21,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
69% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 50%,
"14_ReprPCWk": 36%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: PGR, SMC1A, FOXA2, MEIS1, SS18, NME2, HNF1A, SMAD3, FOXA1, SUZ12, CDK9, HOXB13, ERG, RELA, HDGF, JUNB, ETS1, RUNX2, GRHL3, HIF1A, ARNT, GATA3, GABPA, STAT3, TAL1, ZSCAN4, FOS, ZNF143, MED1, NR3C1, CEBPB, MYB, CREB1, EZH2, LMO2, TP53, ESR1, NFKB1, JUN, TCF12, BAF155, SP1, EP300, NIPBL, AR, NKX2-5, GATA2, EGLN2, BRD4, PHIP, AHR, FOSL2
- Target gene symbol (double-evidenced CRMs): KCNJ6
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 1
- Number of somatic mutations (non-coding): 0
- Related genes and loops