- Basic information
- CohesinDB ID: CDBP00419071
- Locus: chr21-38038950-38040282
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Data sourse: GSE206145-GSE177045, GSE72082, ENCSR000EGW, GSE103477, GSE25021, GSE115602, GSE93080, GSE143937, ENCSR000BKV, GSE138405, GSE76893, GSE206145-NatGen2015, ENCSR703TNG, ENCSR193NSH, ENCSR879KXD, ENCSR981FDC, ENCSR984DZW, ENCSR495WGO, ENCSR000BTQ, GSE105004, GSE111913, ENCSR153HNT, GSE68388, GSE126990, ENCSR000ECS
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Cell type: MCF-7, MDM, Fibroblast, Hela-Kyoto, GM12878, A-549, HeLa-S3, HeLa, RT-112, K-562, HuCC-T1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 9% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.878
- Subunit: SA1,Rad21,SMC1,SA2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
69% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 60%,
"14_ReprPCWk": 35%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: USP7, PGR, GATA2, REST, CBX3, CEBPD, SMARCA4, SMC1A, CTCFL, RAD21, STAG1, CBX1, ESR1, GATA3, ZEB2, HMBOX1, SMC3, CTCF, GATA1, RCOR1
- Target gene symbol (double-evidenced CRMs): KCNJ6
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 8
- Number of somatic mutations (non-coding): 0
- Related genes and loops