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Basic information

CohesinDB ID: CDBP00419076

Locus: chr21-38077039-38077371

Data sourse: GSE120943, ENCSR153HNT, GSE98367

Cell type: K-562, Monocytes, Macrophage

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: SA1,SMC1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 69% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 72%, "14_ReprPCWk": 19%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, PGR, CHD8, CEBPA, MYCN, POU5F1, EZH2phosphoT487, FOXA2, ZFX, SMAD3, ZSCAN5A, HLF, ZBTB33, HOXB13, RELA, ATF3, RAD21, NRF1, PBX4, HIF1A, MAX, TP63, ZSCAN4, FOS, MED1, PLAG1, VDR, CEBPG, CEBPB, NR3C1, NR2F2, TRIM28, CEBPD, TEAD1, TCF7L2, EZH2, ESR1, ZNF334, USF2, JUN, ZHX2, EP300, AR, GATA2, ZNF410, BRD4, JUND, NFIL3, SMC3

Target gene symbol (double-evidenced CRMs): KCNJ6,ERG,DYRK1A

Function elements

Human SNPs: .

Number of somatic mutations (coding): 10

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000157540, ENSG00000157542, ENSG00000157554,

eachgene

Deatailed information for cohesin site CDBP00419076