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Basic information

CohesinDB ID: CDBP00419088

Locus: chr21-38119092-38120170

Data sourse: GSE67783, ENCSR153HNT, ENCSR879KXD

Cell type: K-562, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: SA1,Rad21

CTCF binding site: CTCF CTCF motif: False

Genomic location: TSS

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 69% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 54%, "14_ReprPCWk": 43%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOSL1, PGR, MEIS2, XBP1, FOXA1, SUZ12, RBFOX2, PBX2, UBTF, SIN3B, HDGF, ATF3, NFIC, HNRNPUL1, ATF4, SMARCE1, MITF, ELF1, TRIM28, TEAD1, ETV1, RBM39, NFE2L2, SMAD5, ESR1, SAP30, OCA2, HDAC8, CTCF, JUN, EP300, E4F1, MNT, GATA6, DPF2, TRIM24, RFX5, SOX6, E2F4, DDX20, E2F1, TEAD4, GTF2F1, PDX1, TFAP2C, EHMT2, EED, POU2F2, CHD8, POU5F1, ID3, CTBP1, MTA2, ASH1L, ZBTB48, DUX4, STAT1, ZSCAN5A, NONO, NBN, ARID3A, TBP, PAX6, ERG, MIER1, SMARCC2, MYC, SMARCA4, ARID1B, GRHL3, FOXK2, XRCC5, IKZF1, RCOR1, LEF1, DACH1, NFRKB, NR2F6, NR3C1, CEBPB, ESRRA, ZNF750, CREB1, ZBTB11, EZH2, TBL1XR1, GABPB1, PHF8, ELF4, SPI1, IRF1, ZNF257, HDAC2, GATA2, ZSCAN29, TAF9B, SREBF1, FLI1, HCFC1, NR2C2, MXI1, SMARCA5, EP400, NFYB, MYF5, ATF1, CC2D1A, HDAC1, EZH2phosphoT487, NKX2-2, SIN3A, ZFX, SMAD3, ZMIZ1, IRF2, ZNF384, ZBTB2, BRD9, RUNX2, ARNT, NRF1, TFDP1, PBX4, ATF2, HMBOX1, ZEB2, NFYA, FOXM1, SP2, CHD1, SUPT5H, FOS, MED1, GMEB1, DIDO1, PML, CEBPD, ZMYM3, SMAD1, VEZF1, TAF7, NCOA1, L3MBTL2, C11orf30, USF1, PHF20, REST, ZBTB7A, RBM25, ATF7, ZHX1, HNRNPLL, AFF1, BCOR, MBD2, MLLT1, NFATC3, KLF13, CBX3, MTA3, RBBP5, CREM, MEIS1, E2F8, CHD2, GTF2B, ZBED1, HOXB13, ZKSCAN1, YY1, RELA, JUNB, NEUROD1, ZFP36, SKIL, HIF1A, GATA3, TAL1, MAX, GATA1, MTA1, ZNF143, CBX2, CEBPG, NCOA3, GFI1B, NR2F2, ZNF544, ZNF512, NR2F1, KDM5B, PKNOX1, MYOD1, PHOX2B, BHLHE40, AR, TAF1, ZBTB40, EGLN2, EGR1, MYNN, RNF2, NCOR1, BRD4, JUND, SCRT1, ILF3, CUX1, NOTCH3, MAZ, ZNF24, ZNF316

Target gene symbol (double-evidenced CRMs): KCNJ6

Function elements

Human SNPs: .

Number of somatic mutations (coding): 11

Number of somatic mutations (non-coding): 11

Related genes and loops

Related gene: ENSG00000157542,

eachgene

Deatailed information for cohesin site CDBP00419088