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Basic information

CohesinDB ID: CDBP00419101

Locus: chr21-38179093-38179874

Data sourse: GSE206145-NatGen2015, GSE68388, GSE73207

Cell type: TF-1, Fibroblast, HuCC-T1

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: Mau2,SMC3,SMC1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: non-Hub

Hi-C loops: False Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 69% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 61%, "7_Enh": 18%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOSL1, MEIS2, XBP1, FOXA1, HLF, PBX2, TP63, ELF1, TRIM28, RBM39, KLF6, TP73, CTCF, TCF12, JUN, EP300, GATA6, DPF2, TRIM24, SOX6, TEAD4, TFAP2C, EED, CHD8, ZSCAN5D, ZNF263, BRD3, TOP2A, ZBTB48, ERG2, TBP, ERG, MYC, SMARCA4, ARID1B, RAD21, GRHL3, BATF3, STAT3, IKZF1, RCOR1, NR3C1, CEBPB, EZH2, GABPB1, SPI1, IRF1, GATA2, SIX2, FLI1, RUNX1, CEBPA, ZFX, SMAD3, ERG3, ZNF513, PRDM10, RUNX2, GATA4, ARNT, ZEB2, CBFA2T3, FOS, MED1, NCOA1, SETDB1, BCL11A, REST, BCOR, TCF3, EBF1, MEIS1, CREM, CDK9, RELA, HIF1A, GATA3, BATF, MAF1, TAL1, MAX, ZNF143, GATA1, HAND2, CEBPG, NCOA3, NR2F2, ZNF512, TP53, ZNF334, EGR2, PHOX2B, ELF3, AR, EGR1, HSF1, NCOR1, MYNN, BRD4, JUND, FOSL2

Target gene symbol (double-evidenced CRMs): .

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene:

eachgene

Deatailed information for cohesin site CDBP00419101