- Basic information
- CohesinDB ID: CDBP00419108
- Locus: chr21-38205941-38208380
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Data sourse: GSE206145-GSE177045, GSE67783, GSE86191, GSE98367, GSE206145, GSE206145-NatGen2015, GSE120943
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Cell type: MCF-7, RPE, Fibroblast, HCT-116, Monocytes, HSPC, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.922
- Subunit: Mau2,SA1,Rad21,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
69% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"14_ReprPCWk": 35%,
"15_Quies": 30%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: NME2, KDM4B, FOXA1, HNRNPK, ATF3, THAP1, TRIM28, RBM39, LMO2, ESR1, OCA2, CTCF, TCF12, E2F6, E2F4, TFAP2C, EED, POU2F2, CHD8, BRD1, ZSCAN5D, MYCN, POU5F1, RUNX1T1, TOP2A, ZBTB48, ZSCAN5A, ERG2, ERG, ASCL1, MYC, EZH1, SMARCA4, GRHL3, GABPA, XRCC5, HNRNPH1, NR3C1, EZH2, SPI1, PCBP1, FLI1, HCFC1R1, RUNX1, SMC1A, ZFX, PCBP2, TET2, CREBBP, RUNX2, OSR2, MED1, SP1, REST, ZNF479, SMC3, STAG1, FOXA2, TBL1X, WT1, FOXO3, KDM1A, YY1, RELA, SP140, ZIC2, HIF1A, GATA3, MAX, ZNF143, GATA1, HAND2, PLAG1, NCOA3, NR2F1, KDM5B, TP53, MYOD1, AR, PAX3-FOXO1, HSF1, NCOR1, NOTCH3, BRD4, MAZ, AHR
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 47
- Related genes and loops