Browse_each

Basic information

CohesinDB ID: CDBP00419120

Locus: chr21-38237989-38238652

Data sourse: GSE67783, GSE86191, GSE111913, GSE206145, GSE126755

Cell type: RPE, HCT-116, RT-112, Neutrophil, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.944

Subunit: SA1,Rad21,SMC1

CTCF binding site: CTCF CTCF motif: False

Genomic location: TSS,TES

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 69% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 73%, "5_TxWk": 13%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: PGR, XBP1, HNF1A, FOXA1, HLF, ATF3, NFIC, RUNX3, CBFB, PAX5, HDAC3, CDX2, TEAD1, BCLAF1, TRIM28, KLF6, ETV1, ESR1, OCA2, HNF1B, TP73, JUN, CTCF, TCF12, BAF155, PAX8, E2F1, TEAD4, TFAP2C, POU2F2, CHD8, MYCN, POU5F1, TOP2A, KDM4C, BRD3, ZBTB48, ERG, MYC, ONECUT1, RAD21, GRHL3, RXRA, GABPA, STAT3, NKX3-1, IKZF1, NR3C1, CEBPB, EZH2, GRHL2, ZHX2, SPI1, IRF1, GATA2, SIX2, HCFC1R1, RUNX1, SMC1A, ZFX, SMAD3, TET2, ZNF770, CREBBP, NOTCH1, RUNX2, ARNT, NRF1, FOS, MED1, ZEB1, TERF1, MYB, SCRT2, PIAS1, BCL11A, SP1, GSPT2, HNF4A, REST, ARID1A, ASH2L, SMC3, STAG1, STAG2, PPARG, TBL1X, MEIS1, SS18, WT1, MEF2C, CDK9, HOXB13, KDM1A, YY1, RELA, BRG1, SP140, HIF1A, GATA3, TAL1, MAX, ZNF143, TLE3, KLF4, KDM5B, NFKB1, MYOD1, ELF3, TBX21, PAX3-FOXO1, AR, NOTCH3, BRD4, SCRT1, MAZ

Target gene symbol (double-evidenced CRMs): VPS26C

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 3

Related genes and loops

Related gene: ENSG00000157538,

eachgene

Deatailed information for cohesin site CDBP00419120